Hydrogel-based sealed microchambers for simple and cost-effective cell culture and drug testing

Shotaro Yoshida, Kensuke Sumomozawa, Matsuhiko Nishizawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We propose a hydrogel-based sealed microchamber that enables easy and simple cell culture and drug testing. Cells can be cultured inside the sealed microchambers for the permeability of the hydrogel microchambers to nutrients. Also, drug testing from outside the sealed microchamber is demonstrated. The molecularly permeable, sealed microchambers enables simple and cost-effective medium exchange during cell culture and drug testing with cells stably positioned, which is useful in culturing floating cell spheroids for regenerative medicine and drug testing.

Original languageEnglish
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PublisherChemical and Biological Microsystems Society
Pages1504-1505
Number of pages2
ISBN (Electronic)9781733419000
Publication statusPublished - 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
Duration: 2019 Oct 272019 Oct 31

Publication series

Name23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
CountrySwitzerland
CityBasel
Period19/10/2719/10/31

Keywords

  • Cardiomyocytes
  • HiPSC
  • Hydrogel
  • Molecular permeability
  • Organic electronics

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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