Human parvovirus B19 infection during the inactive stage of systemic lupus erythematosus

Takashiro Suzuki, Shinichiro Saito, Yasuhiko Hirabayashi, Hideo Harigae, Tomonori Ishii, Takao Kodera, Hiroshi Fujii, Yasuhiko Munakata, Takeshi Sasaki

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A 42-year-old woman with systemic lupus erythematosus (SLE) had an episode of fever, arthralgia and anemia. In order to treat the suspected activation of SLE, the daily dose of steroid was increased, however, the anemia progressed and pancytopenia developed. Both IgM anti-B19 antibodies to human parvovirus B19 (B19) and B19 DNA were positive, and bone marrow analysis revealed pure red cell aplasia with giant proerythroblasts. High dose γ globulin was administered and the daily dose of steroid was tapered, resulting in the improvement of her condition. B19 infection should be ruled out in cases with reactivation of autoimmune diseases.

Original languageEnglish
Pages (from-to)538-540
Number of pages3
JournalInternal Medicine
Volume42
Issue number6
DOIs
Publication statusPublished - 2003 Jun 1

Keywords

  • Anemia
  • Human parvovirus B19
  • Systemic lupus erythematosus
  • γ globulin

ASJC Scopus subject areas

  • Internal Medicine

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