TY - JOUR
T1 - Human parvovirus B19 infection during the inactive stage of systemic lupus erythematosus
AU - Suzuki, Takashiro
AU - Saito, Shinichiro
AU - Hirabayashi, Yasuhiko
AU - Harigae, Hideo
AU - Ishii, Tomonori
AU - Kodera, Takao
AU - Fujii, Hiroshi
AU - Munakata, Yasuhiko
AU - Sasaki, Takeshi
PY - 2003/6/1
Y1 - 2003/6/1
N2 - A 42-year-old woman with systemic lupus erythematosus (SLE) had an episode of fever, arthralgia and anemia. In order to treat the suspected activation of SLE, the daily dose of steroid was increased, however, the anemia progressed and pancytopenia developed. Both IgM anti-B19 antibodies to human parvovirus B19 (B19) and B19 DNA were positive, and bone marrow analysis revealed pure red cell aplasia with giant proerythroblasts. High dose γ globulin was administered and the daily dose of steroid was tapered, resulting in the improvement of her condition. B19 infection should be ruled out in cases with reactivation of autoimmune diseases.
AB - A 42-year-old woman with systemic lupus erythematosus (SLE) had an episode of fever, arthralgia and anemia. In order to treat the suspected activation of SLE, the daily dose of steroid was increased, however, the anemia progressed and pancytopenia developed. Both IgM anti-B19 antibodies to human parvovirus B19 (B19) and B19 DNA were positive, and bone marrow analysis revealed pure red cell aplasia with giant proerythroblasts. High dose γ globulin was administered and the daily dose of steroid was tapered, resulting in the improvement of her condition. B19 infection should be ruled out in cases with reactivation of autoimmune diseases.
KW - Anemia
KW - Human parvovirus B19
KW - Systemic lupus erythematosus
KW - γ globulin
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U2 - 10.2169/internalmedicine.42.538
DO - 10.2169/internalmedicine.42.538
M3 - Article
C2 - 12857057
AN - SCOPUS:0041670945
VL - 42
SP - 538
EP - 540
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 6
ER -