Human leucocyte antigen and coronary artery spasm

Hiroaki Shimokawa, Kiyokazu Toyoda, Takahiro Matsumoto, Hiroyuki Sato, Yutaka Kikuchi, Motoomi Nakamura

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


To elucidate possible genetic links in the pathogenesis of coronary artery spasm, we investigated the frequencies of human leucocyte antigen in 37 patients with variant angina and 236 unrelated healthy controls. We found no significant differences in human leucocyte antigen frequencies between the patients and the controls. These results may suggest that genetic factors in linkage disequilibrium with human leucocyte antigen may not be involved in the pathogenesis of coronary artery spasm.

Original languageEnglish
Pages (from-to)362-365
Number of pages4
JournalInternational Journal of Cardiology
Issue number3
Publication statusPublished - 1986 Sep
Externally publishedYes


  • coronary spasm
  • human leucocyte antigen
  • variant angina

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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