Human leucocyte antigen and coronary artery spasm

Hiroaki Shimokawa; Kiyokazu Toyoda; Takahiro Matsumoto; Hiroyuki Sato; Yutaka Kikuchi; Motoomi Nakamura

doi:10.1016/0167-5273(86)90273-1

Human leucocyte antigen and coronary artery spasm

Hiroaki Shimokawa, Kiyokazu Toyoda, Takahiro Matsumoto, Hiroyuki Sato, Yutaka Kikuchi, Motoomi Nakamura

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

To elucidate possible genetic links in the pathogenesis of coronary artery spasm, we investigated the frequencies of human leucocyte antigen in 37 patients with variant angina and 236 unrelated healthy controls. We found no significant differences in human leucocyte antigen frequencies between the patients and the controls. These results may suggest that genetic factors in linkage disequilibrium with human leucocyte antigen may not be involved in the pathogenesis of coronary artery spasm.

Original language	English
Pages (from-to)	362-365
Number of pages	4
Journal	International Journal of Cardiology
Volume	12
Issue number	3
DOIs	https://doi.org/10.1016/0167-5273(86)90273-1
Publication status	Published - 1986 Sep

Keywords

coronary spasm
human leucocyte antigen
variant angina

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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title = "Human leucocyte antigen and coronary artery spasm",

abstract = "To elucidate possible genetic links in the pathogenesis of coronary artery spasm, we investigated the frequencies of human leucocyte antigen in 37 patients with variant angina and 236 unrelated healthy controls. We found no significant differences in human leucocyte antigen frequencies between the patients and the controls. These results may suggest that genetic factors in linkage disequilibrium with human leucocyte antigen may not be involved in the pathogenesis of coronary artery spasm.",

keywords = "coronary spasm, human leucocyte antigen, variant angina",

author = "Hiroaki Shimokawa and Kiyokazu Toyoda and Takahiro Matsumoto and Hiroyuki Sato and Yutaka Kikuchi and Motoomi Nakamura",

year = "1986",

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T1 - Human leucocyte antigen and coronary artery spasm

AU - Shimokawa, Hiroaki

AU - Toyoda, Kiyokazu

AU - Matsumoto, Takahiro

AU - Sato, Hiroyuki

AU - Kikuchi, Yutaka

AU - Nakamura, Motoomi

PY - 1986/9

Y1 - 1986/9

N2 - To elucidate possible genetic links in the pathogenesis of coronary artery spasm, we investigated the frequencies of human leucocyte antigen in 37 patients with variant angina and 236 unrelated healthy controls. We found no significant differences in human leucocyte antigen frequencies between the patients and the controls. These results may suggest that genetic factors in linkage disequilibrium with human leucocyte antigen may not be involved in the pathogenesis of coronary artery spasm.

AB - To elucidate possible genetic links in the pathogenesis of coronary artery spasm, we investigated the frequencies of human leucocyte antigen in 37 patients with variant angina and 236 unrelated healthy controls. We found no significant differences in human leucocyte antigen frequencies between the patients and the controls. These results may suggest that genetic factors in linkage disequilibrium with human leucocyte antigen may not be involved in the pathogenesis of coronary artery spasm.

KW - coronary spasm

KW - human leucocyte antigen

KW - variant angina

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JO - International Journal of Cardiology

JF - International Journal of Cardiology

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