Human cortical anatomical networks assessed by structural MRI

A. C. Evans, J. M. Lee, S. I. Kim, H. Fukuda, R. Kawashima, Y. He, T. Jiang, J. S. Kim, Z. Chen, K. Im, O. Lyttelton, J. Lerch, V. Singh, K. Sato, Y. Taki, R. Goto, S. Kinomura, K. Mok, J. K. Lee, U. Yoon

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Mapping the structure and function of the brain with non-invasive brain imaging techniques has become a world-wide enterpise in the last 20 years. The core concept that drives this rapid growth has been the use of a standardized 3D coordinate space for combining data from many subjects and/or time-points. This has allowed geographically-separated laboratories to reproduce experiments in precise detail, to share data or to perform meta-analysis in ways that go far beyond the traditional reviewing of summary results in journal publications. A further corollary of the brain mapping approach is the natural fostering of multi-center collaboration among distant sites. This article describes recent progress in trans-Pacific collaboration between Canadian and Asian laboratories in the study of neuroanatomical networks obtained from MRI data, both in the normal brain and in neurodegenerative disorders.

Original languageEnglish
Pages (from-to)289-299
Number of pages11
JournalBrain Imaging and Behavior
Issue number4
Publication statusPublished - 2008 Dec


  • Alzheimer's disease
  • Brain mapping
  • Brain networks
  • Cortical thickness
  • Leukoaraiosis
  • Multiple Sclerosis
  • Pacific rim
  • Small-world

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology
  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience
  • Psychiatry and Mental health
  • Behavioral Neuroscience


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