Human carcinoma: Early experience with phase-contrast x-ray CT with synchrotron radiation - Comparative specimen study with optical microscopy

Tohoru Takeda, Atsushi Momose, Kelichi Hirano, Seiji Haraoka, Teruo Watanabe, Yuji Ital

Research output: Contribution to journalArticlepeer-review

111 Citations (Scopus)

Abstract

Phase-contrast x-ray computed tomography (CT) indicates the distribution of the refractive index and has potential to reveal the structures inside soft tissues without a contrast agent. With a synchrotron x-ray source, phase-contrast x-ray CT with a triple Laue-case x-ray interferometer clearly differentiated various human pathologic tissues in the cases of hepatocellular carcinoma with cirrhosis and metastatic colon carcinoma to the liver, and the images closely corresponded to those obtained with low- magnification optical microscopy.

Original languageEnglish
Pages (from-to)298-301
Number of pages4
JournalRadiology
Volume214
Issue number1
DOIs
Publication statusPublished - 2000
Externally publishedYes

Keywords

  • Computed tomography (CT), phase imaging
  • Computed tomography (CT), technology
  • Computed tomography (CT), tissue characterization
  • Synchrotron

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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