Hroth, an orthodenticle-related homeobox gene of the ascidian, Halocynthia roretzi: Its expression and putative roles in the axis formation during embryogenesis

Shuichi Wada; You Katsuyama; Yoshiko Sato; Chieko Itoh; Hidetoshi Saiga

doi:10.1016/S0925-4773(96)00600-4

Hroth, an orthodenticle-related homeobox gene of the ascidian, Halocynthia roretzi: Its expression and putative roles in the axis formation during embryogenesis

Shuichi Wada, You Katsuyama, Yoshiko Sato, Chieko Itoh, Hidetoshi Saiga

Research output: Contribution to journal › Article › peer-review

112 Citations (Scopus)

Abstract

To obtain insight into the axis-forming mechanism in ascidian embryogenesis, Hroth, an ascidian counterpart of orthodenticlelotx, was isolated from Halocynthia roretzi and its expression in embryogenesis was examined by whole mount in situ hybridization. It was revealed that Hroth is expressed in both involuting mesoendoderm and anterior ectoderm during gastrulation while later expression is restricted to the sensory vesicle and anterior epidermis. Expression pattern of Hroth around gastrulation was compared with that of Hrlim, the ascidian LIM class homeobox gene that is known to be expressed during gastrulation. In the light of the present findings on the expression of Hroth, properties of the axis-forming mechanism in ascidian embryogenesis are discussed.

Original language	English
Pages (from-to)	59-71
Number of pages	13
Journal	Mechanisms of Development
Volume	60
Issue number	1
DOIs	https://doi.org/10.1016/S0925-4773(96)00600-4
Publication status	Published - 1996 Nov

Keywords

Ascidian
Body axis formation
Gastrulation
Orthodenticle

ASJC Scopus subject areas

Embryology
Developmental Biology

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Hroth, an orthodenticle-related homeobox gene of the ascidian, Halocynthia roretzi : Its expression and putative roles in the axis formation during embryogenesis. / Wada, Shuichi; Katsuyama, You; Sato, Yoshiko; Itoh, Chieko; Saiga, Hidetoshi.

In: Mechanisms of Development, Vol. 60, No. 1, 11.1996, p. 59-71.

Research output: Contribution to journal › Article › peer-review

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title = "Hroth, an orthodenticle-related homeobox gene of the ascidian, Halocynthia roretzi: Its expression and putative roles in the axis formation during embryogenesis",

abstract = "To obtain insight into the axis-forming mechanism in ascidian embryogenesis, Hroth, an ascidian counterpart of orthodenticlelotx, was isolated from Halocynthia roretzi and its expression in embryogenesis was examined by whole mount in situ hybridization. It was revealed that Hroth is expressed in both involuting mesoendoderm and anterior ectoderm during gastrulation while later expression is restricted to the sensory vesicle and anterior epidermis. Expression pattern of Hroth around gastrulation was compared with that of Hrlim, the ascidian LIM class homeobox gene that is known to be expressed during gastrulation. In the light of the present findings on the expression of Hroth, properties of the axis-forming mechanism in ascidian embryogenesis are discussed.",

keywords = "Ascidian, Body axis formation, Gastrulation, Orthodenticle",

author = "Shuichi Wada and You Katsuyama and Yoshiko Sato and Chieko Itoh and Hidetoshi Saiga",

note = "Funding Information: The authors wish to thank Dr. Numakunai, Asamushi Marine Biological Station, Tohoku University and staffs in Otuchi Marine Research Center, University of Tokyo for providing us with research facilities. The authors thank Drs. Paul J. Scatting, University of Nottingham, UK and Sadao Yasugi for critical reading of the manuscript. This work was supported by Grants-in-Aid for Scientific Researcho n Priority Areas from the Ministry of Education, Science and Culture of Japan and by Fund for Special Research Project at Tokyo Metropolitan University to H.S.",

year = "1996",

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doi = "10.1016/S0925-4773(96)00600-4",

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AU - Sato, Yoshiko

AU - Itoh, Chieko

AU - Saiga, Hidetoshi

N1 - Funding Information: The authors wish to thank Dr. Numakunai, Asamushi Marine Biological Station, Tohoku University and staffs in Otuchi Marine Research Center, University of Tokyo for providing us with research facilities. The authors thank Drs. Paul J. Scatting, University of Nottingham, UK and Sadao Yasugi for critical reading of the manuscript. This work was supported by Grants-in-Aid for Scientific Researcho n Priority Areas from the Ministry of Education, Science and Culture of Japan and by Fund for Special Research Project at Tokyo Metropolitan University to H.S.

PY - 1996/11

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N2 - To obtain insight into the axis-forming mechanism in ascidian embryogenesis, Hroth, an ascidian counterpart of orthodenticlelotx, was isolated from Halocynthia roretzi and its expression in embryogenesis was examined by whole mount in situ hybridization. It was revealed that Hroth is expressed in both involuting mesoendoderm and anterior ectoderm during gastrulation while later expression is restricted to the sensory vesicle and anterior epidermis. Expression pattern of Hroth around gastrulation was compared with that of Hrlim, the ascidian LIM class homeobox gene that is known to be expressed during gastrulation. In the light of the present findings on the expression of Hroth, properties of the axis-forming mechanism in ascidian embryogenesis are discussed.

AB - To obtain insight into the axis-forming mechanism in ascidian embryogenesis, Hroth, an ascidian counterpart of orthodenticlelotx, was isolated from Halocynthia roretzi and its expression in embryogenesis was examined by whole mount in situ hybridization. It was revealed that Hroth is expressed in both involuting mesoendoderm and anterior ectoderm during gastrulation while later expression is restricted to the sensory vesicle and anterior epidermis. Expression pattern of Hroth around gastrulation was compared with that of Hrlim, the ascidian LIM class homeobox gene that is known to be expressed during gastrulation. In the light of the present findings on the expression of Hroth, properties of the axis-forming mechanism in ascidian embryogenesis are discussed.

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Hroth, an orthodenticle-related homeobox gene of the ascidian, Halocynthia roretzi: Its expression and putative roles in the axis formation during embryogenesis

Abstract

Keywords

ASJC Scopus subject areas

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