Hroth, an orthodenticle-related homeobox gene of the ascidian, Halocynthia roretzi: Its expression and putative roles in the axis formation during embryogenesis

Shuichi Wada, You Katsuyama, Yoshiko Sato, Chieko Itoh, Hidetoshi Saiga

    Research output: Contribution to journalArticle

    112 Citations (Scopus)

    Abstract

    To obtain insight into the axis-forming mechanism in ascidian embryogenesis, Hroth, an ascidian counterpart of orthodenticlelotx, was isolated from Halocynthia roretzi and its expression in embryogenesis was examined by whole mount in situ hybridization. It was revealed that Hroth is expressed in both involuting mesoendoderm and anterior ectoderm during gastrulation while later expression is restricted to the sensory vesicle and anterior epidermis. Expression pattern of Hroth around gastrulation was compared with that of Hrlim, the ascidian LIM class homeobox gene that is known to be expressed during gastrulation. In the light of the present findings on the expression of Hroth, properties of the axis-forming mechanism in ascidian embryogenesis are discussed.

    Original languageEnglish
    Pages (from-to)59-71
    Number of pages13
    JournalMechanisms of Development
    Volume60
    Issue number1
    DOIs
    Publication statusPublished - 1996 Nov 1

    Keywords

    • Ascidian
    • Body axis formation
    • Gastrulation
    • Orthodenticle

    ASJC Scopus subject areas

    • Embryology
    • Developmental Biology

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