How far have we come in terms of estrogens in breast cancer?

Keely May McNamara, Fouzia Guestini, Minako Sakurai, Kyoko Kikuchi, Hironobu Sasano

Research output: Contribution to journalReview articlepeer-review

7 Citations (Scopus)

Abstract

Major advances in breast cancer treatment have almost always been linked to the actions of estrogen. Therefore, this review focused on estrogen actions in the breast, particularly the developments of the past 20 years, the present understanding of disease biology and possible future developments. Within these areas have focused on what is known about the underlying molecular biology and in particular integration of the bioinformatics revolution of the last 15 years with other facets of research. In addition, there will be an emphasis on the understanding brought about by a greater appreciation for the intracrinology of the breast.

Original languageEnglish
Pages (from-to)413-424
Number of pages12
Journalendocrine journal
Volume63
Issue number5
DOIs
Publication statusPublished - 2016
Externally publishedYes

Keywords

  • Breast cancer
  • Hormone receptors
  • Hormones
  • Sex steroid

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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