Homology between the photoreactivation genes of Saccharomyces cerevisiae and Escherichia coli

Akira Yasui, Simon A. Langeveld

    Research output: Contribution to journalArticlepeer-review

    18 Citations (Scopus)

    Abstract

    A cloned fragment of Saccharomyces cerevisiae chromosomal DNA carrying the photoreactivation gene (PHR) has been sequenced. The fragment contains a 1695-bp intronless open reading frame (ORF) coding for a polypeptide of 564 amino acids (aa). The phr gene of Escherichia coli was also sequenced, and the sequence is in agreement with the published data. The yeast PHR gene has a G + C content of 36.2%, whereas 53.7% was found for the E. coli gene. Despite the difference in G + C content there is a 35% homology between the deduced aa sequences. This homology suggests that both genes have originated from a common ancestral gene.

    Original languageEnglish
    Pages (from-to)349-355
    Number of pages7
    JournalGene
    Volume36
    Issue number3
    DOIs
    Publication statusPublished - 1985

    Keywords

    • (Recombinant DNA
    • computer-aided comparison
    • nucleotide sequence
    • open reading frame
    • photolyase)
    • plasmid vector
    • ultraviolet light
    • yeast

    ASJC Scopus subject areas

    • Genetics

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