Hollow fiber-optic Raman probes for small experimental animals

Takashi Katagiri, Yusuke Hattori, Toshiaki Suzuki, Yuji Matsuura, Hidetoshi Sato

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Two types of hollow fiber-optic probes are developed to measure the in vivo Raman spectra of small animals. One is the minimized probe which is end-sealed with the micro-ball lens. The measured spectra reflect the information of the sample's sub-surface. This probe is used for the measurement of the esophagus and the stomach via an endoscope. The other probe is a confocal Raman probe which consists of a single fiber and a lens system. It is integrated into the handheld microscope. A simple and small multimodal probe is realized because the hollow optical fiber requires no optical filters. The performance of each probe is examined and the effectiveness of these probes for in vivo Raman spectroscopy is shown by animal tests.

Original languageEnglish
Title of host publicationOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications VII
DOIs
Publication statusPublished - 2007 Apr 30
EventOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications VII - San Jose, CA, United States
Duration: 2007 Jan 202007 Jan 21

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6433
ISSN (Print)1605-7422

Other

OtherOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications VII
CountryUnited States
CitySan Jose, CA
Period07/1/2007/1/21

Keywords

  • Fiber-optic probe
  • Hollow optical fiber
  • Raman spectroscopy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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