Hollow fiber based SERS probe for analysis of biological molecules

M. Nagaoka; T. Katagiri; Y. Matsuura

doi:10.1117/12.2039185

Hollow fiber based SERS probe for analysis of biological molecules

M. Nagaoka, T. Katagiri, Y. Matsuura

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A flexible fiber probe for surface-enhanced Raman scattering (SERS) was fabricated by forming gold nanostructures on a ball lens mounted at the distal end of a hollow optical fiber. Two different methods were used to form the gold nanoparticles. In the photochemical deposition, easily fabricated probe indicated good sensitivity, but low reproducibility. On the other hand, in the sputtering method, higher intensity was achieved constantly because an optimal forming condition can be strictly controlled. The measurement of biological molecules using fabricated SERS active probe is also demonstrated.

Original language	English
Title of host publication	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV
Publisher	SPIE
ISBN (Print)	9780819498519
DOIs	https://doi.org/10.1117/12.2039185
Publication status	Published - 2014
Event	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV - San Francisco, CA, United States Duration: 2014 Feb 1 → 2014 Feb 2

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	8938
ISSN (Print)	1605-7422

Other

Other	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV
Country	United States
City	San Francisco, CA
Period	14/2/1 → 14/2/2

Keywords

Hollow optical fiber
Raman spectroscopy
Surface-enhanced Raman scattering (SERS)

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

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Hollow fiber based SERS probe for analysis of biological molecules. / Nagaoka, M.; Katagiri, T.; Matsuura, Y.

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV. SPIE, 2014. 89380Y (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8938).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Nagaoka, M, Katagiri, T & Matsuura, Y 2014, Hollow fiber based SERS probe for analysis of biological molecules. in Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV., 89380Y, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8938, SPIE, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV, San Francisco, CA, United States, 14/2/1. https://doi.org/10.1117/12.2039185

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title = "Hollow fiber based SERS probe for analysis of biological molecules",

abstract = "A flexible fiber probe for surface-enhanced Raman scattering (SERS) was fabricated by forming gold nanostructures on a ball lens mounted at the distal end of a hollow optical fiber. Two different methods were used to form the gold nanoparticles. In the photochemical deposition, easily fabricated probe indicated good sensitivity, but low reproducibility. On the other hand, in the sputtering method, higher intensity was achieved constantly because an optimal forming condition can be strictly controlled. The measurement of biological molecules using fabricated SERS active probe is also demonstrated.",

keywords = "Hollow optical fiber, Raman spectroscopy, Surface-enhanced Raman scattering (SERS)",

author = "M. Nagaoka and T. Katagiri and Y. Matsuura",

note = "Copyright: Copyright 2014 Elsevier B.V., All rights reserved.; Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV ; Conference date: 01-02-2014 Through 02-02-2014",

year = "2014",

doi = "10.1117/12.2039185",

language = "English",

isbn = "9780819498519",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

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AU - Nagaoka, M.

AU - Katagiri, T.

AU - Matsuura, Y.

PY - 2014

Y1 - 2014

N2 - A flexible fiber probe for surface-enhanced Raman scattering (SERS) was fabricated by forming gold nanostructures on a ball lens mounted at the distal end of a hollow optical fiber. Two different methods were used to form the gold nanoparticles. In the photochemical deposition, easily fabricated probe indicated good sensitivity, but low reproducibility. On the other hand, in the sputtering method, higher intensity was achieved constantly because an optimal forming condition can be strictly controlled. The measurement of biological molecules using fabricated SERS active probe is also demonstrated.

AB - A flexible fiber probe for surface-enhanced Raman scattering (SERS) was fabricated by forming gold nanostructures on a ball lens mounted at the distal end of a hollow optical fiber. Two different methods were used to form the gold nanoparticles. In the photochemical deposition, easily fabricated probe indicated good sensitivity, but low reproducibility. On the other hand, in the sputtering method, higher intensity was achieved constantly because an optimal forming condition can be strictly controlled. The measurement of biological molecules using fabricated SERS active probe is also demonstrated.

KW - Hollow optical fiber

KW - Raman spectroscopy

KW - Surface-enhanced Raman scattering (SERS)

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M3 - Conference contribution

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SN - 9780819498519

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV

PB - SPIE

T2 - Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV

Y2 - 1 February 2014 through 2 February 2014

ER -

Hollow fiber based SERS probe for analysis of biological molecules

Abstract

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Keywords

ASJC Scopus subject areas

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