Hollow fiber based SERS probe for analysis of biological molecules

M. Nagaoka; T. Katagiri; Y. Matsuura

doi:10.1117/12.2039185

Hollow fiber based SERS probe for analysis of biological molecules

M. Nagaoka, T. Katagiri, Y. Matsuura

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A flexible fiber probe for surface-enhanced Raman scattering (SERS) was fabricated by forming gold nanostructures on a ball lens mounted at the distal end of a hollow optical fiber. Two different methods were used to form the gold nanoparticles. In the photochemical deposition, easily fabricated probe indicated good sensitivity, but low reproducibility. On the other hand, in the sputtering method, higher intensity was achieved constantly because an optimal forming condition can be strictly controlled. The measurement of biological molecules using fabricated SERS active probe is also demonstrated.

Original language	English
Title of host publication	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV
Publisher	SPIE
ISBN (Print)	9780819498519
DOIs	https://doi.org/10.1117/12.2039185
Publication status	Published - 2014 Jan 1
Event	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV - San Francisco, CA, United States Duration: 2014 Feb 1 → 2014 Feb 2

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	8938
ISSN (Print)	1605-7422

Other

Other	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV
Country	United States
City	San Francisco, CA
Period	14/2/1 → 14/2/2

Keywords

Hollow optical fiber
Raman spectroscopy
Surface-enhanced Raman scattering (SERS)

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

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10.1117/12.2039185

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Nagaoka, M., Katagiri, T., & Matsuura, Y. (2014). Hollow fiber based SERS probe for analysis of biological molecules. In Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV [89380Y] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8938). SPIE. https://doi.org/10.1117/12.2039185

Hollow fiber based SERS probe for analysis of biological molecules. / Nagaoka, M.; Katagiri, T.; Matsuura, Y.

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV. SPIE, 2014. 89380Y (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8938).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Nagaoka, M, Katagiri, T & Matsuura, Y 2014, Hollow fiber based SERS probe for analysis of biological molecules. in Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV., 89380Y, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8938, SPIE, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV, San Francisco, CA, United States, 14/2/1. https://doi.org/10.1117/12.2039185

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