Hollow fiber based SERS probe for analysis of biological molecules

M. Nagaoka, T. Katagiri, Y. Matsuura

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A flexible fiber probe for surface-enhanced Raman scattering (SERS) was fabricated by forming gold nanostructures on a ball lens mounted at the distal end of a hollow optical fiber. Two different methods were used to form the gold nanoparticles. In the photochemical deposition, easily fabricated probe indicated good sensitivity, but low reproducibility. On the other hand, in the sputtering method, higher intensity was achieved constantly because an optimal forming condition can be strictly controlled. The measurement of biological molecules using fabricated SERS active probe is also demonstrated.

Original languageEnglish
Title of host publicationOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV
PublisherSPIE
ISBN (Print)9780819498519
DOIs
Publication statusPublished - 2014 Jan 1
EventOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV - San Francisco, CA, United States
Duration: 2014 Feb 12014 Feb 2

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8938
ISSN (Print)1605-7422

Other

OtherOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV
CountryUnited States
CitySan Francisco, CA
Period14/2/114/2/2

Keywords

  • Hollow optical fiber
  • Raman spectroscopy
  • Surface-enhanced Raman scattering (SERS)

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Hollow fiber based SERS probe for analysis of biological molecules'. Together they form a unique fingerprint.

  • Cite this

    Nagaoka, M., Katagiri, T., & Matsuura, Y. (2014). Hollow fiber based SERS probe for analysis of biological molecules. In Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV [89380Y] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8938). SPIE. https://doi.org/10.1117/12.2039185