TY - GEN
T1 - Hollow fiber based SERS probe for analysis of biological molecules
AU - Nagaoka, M.
AU - Katagiri, T.
AU - Matsuura, Y.
PY - 2014
Y1 - 2014
N2 - A flexible fiber probe for surface-enhanced Raman scattering (SERS) was fabricated by forming gold nanostructures on a ball lens mounted at the distal end of a hollow optical fiber. Two different methods were used to form the gold nanoparticles. In the photochemical deposition, easily fabricated probe indicated good sensitivity, but low reproducibility. On the other hand, in the sputtering method, higher intensity was achieved constantly because an optimal forming condition can be strictly controlled. The measurement of biological molecules using fabricated SERS active probe is also demonstrated.
AB - A flexible fiber probe for surface-enhanced Raman scattering (SERS) was fabricated by forming gold nanostructures on a ball lens mounted at the distal end of a hollow optical fiber. Two different methods were used to form the gold nanoparticles. In the photochemical deposition, easily fabricated probe indicated good sensitivity, but low reproducibility. On the other hand, in the sputtering method, higher intensity was achieved constantly because an optimal forming condition can be strictly controlled. The measurement of biological molecules using fabricated SERS active probe is also demonstrated.
KW - Hollow optical fiber
KW - Raman spectroscopy
KW - Surface-enhanced Raman scattering (SERS)
UR - http://www.scopus.com/inward/record.url?scp=84897380191&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84897380191&partnerID=8YFLogxK
U2 - 10.1117/12.2039185
DO - 10.1117/12.2039185
M3 - Conference contribution
AN - SCOPUS:84897380191
SN - 9780819498519
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV
PB - SPIE
T2 - Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV
Y2 - 1 February 2014 through 2 February 2014
ER -