Abstract
We report on highly selective binding of a naphthyridine derivative with a trifluoromethyl group to cytosine opposite an abasic site in DNA duplexes; the binding-induced fluorescence quenching is applicable to the analysis of a C-related single-base mutation in DNAs amplified by PCR.
Original language | English |
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Pages (from-to) | 4003-4006 |
Number of pages | 4 |
Journal | Organic and Biomolecular Chemistry |
Volume | 10 |
Issue number | 20 |
DOIs | |
Publication status | Published - 2012 May 28 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry