(matrix presented) Excellent enantioselectivities up to 99.7% were achieved in the hydrogenation of (E)-β-(acylamino)acrylates by the use of Rh(I)-complexes of electron-rich diphosphines, t-Bu-BisP* and t-Bu-MiniPHOS. Low-temperature NMR experiments testify that monohydrides with β-carbon atom of the substrate bound to rhodium are involved in the catalytic cycle.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry