Highly enantioselective addition of dialkylzincs to aldehydes using dendritic chiral catalysts with flexible carbosilane backbones

Itaru Sato; Ryo Kodaka; Kenji Hosoi; Kenso Soai

doi:10.1016/S0957-4166(02)00203-3

Highly enantioselective addition of dialkylzincs to aldehydes using dendritic chiral catalysts with flexible carbosilane backbones

Itaru Sato, Ryo Kodaka, Kenji Hosoi, Kenso Soai

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

Chiral dendrimers bearing four or twelve chiral β-amino alcohols on the hyperbranched flexible carbosilane chain-ends act as efficient chiral catalysts for the enantioselective addition of dialkylzinc to aldehydes to afford enantiomerically enriched sec-alcohols with up to 93% e.e.

Original language	English
Pages (from-to)	805-808
Number of pages	4
Journal	Tetrahedron Asymmetry
Volume	13
Issue number	8
DOIs	https://doi.org/10.1016/S0957-4166(02)00203-3
Publication status	Published - 2002 May 15
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.1016/S0957-4166(02)00203-3

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title = "Highly enantioselective addition of dialkylzincs to aldehydes using dendritic chiral catalysts with flexible carbosilane backbones",

abstract = "Chiral dendrimers bearing four or twelve chiral β-amino alcohols on the hyperbranched flexible carbosilane chain-ends act as efficient chiral catalysts for the enantioselective addition of dialkylzinc to aldehydes to afford enantiomerically enriched sec-alcohols with up to 93% e.e.",

author = "Itaru Sato and Ryo Kodaka and Kenji Hosoi and Kenso Soai",

note = "Funding Information: This work was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan and by Japan Space Forum.",

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T1 - Highly enantioselective addition of dialkylzincs to aldehydes using dendritic chiral catalysts with flexible carbosilane backbones

AU - Sato, Itaru

AU - Kodaka, Ryo

AU - Hosoi, Kenji

AU - Soai, Kenso

N1 - Funding Information: This work was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan and by Japan Space Forum.

PY - 2002/5/15

Y1 - 2002/5/15

N2 - Chiral dendrimers bearing four or twelve chiral β-amino alcohols on the hyperbranched flexible carbosilane chain-ends act as efficient chiral catalysts for the enantioselective addition of dialkylzinc to aldehydes to afford enantiomerically enriched sec-alcohols with up to 93% e.e.

AB - Chiral dendrimers bearing four or twelve chiral β-amino alcohols on the hyperbranched flexible carbosilane chain-ends act as efficient chiral catalysts for the enantioselective addition of dialkylzinc to aldehydes to afford enantiomerically enriched sec-alcohols with up to 93% e.e.

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JO - Tetrahedron Asymmetry

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ER -

Highly enantioselective addition of dialkylzincs to aldehydes using dendritic chiral catalysts with flexible carbosilane backbones

Abstract

ASJC Scopus subject areas

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