Highly efficient synthesis of medium-sized lactones via oxidative lactonization: Concise total synthesis of isolaurepanf

Makoto Ebine, Yuto Suga, Haruhiko Fuwa, Makoto Sasaki

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

A catalytic amount of TEMPO in the presence of PhI(OAc)2 effected oxidative lactonization of 1,6- and 1,7-diols, directly affording seven- and eight-membered lactones, respectively, in good yields.

Original languageEnglish
Pages (from-to)39-42
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume8
Issue number1
DOIs
Publication statusPublished - 2010 Feb 23

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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