Highly efficient synthesis of medium-sized lactones via oxidative lactonization: Concise total synthesis of isolaurepanf

Makoto Ebine, Yuto Suga, Haruhiko Fuwa, Makoto Sasaki

    Research output: Contribution to journalArticlepeer-review

    32 Citations (Scopus)

    Abstract

    A catalytic amount of TEMPO in the presence of PhI(OAc)2 effected oxidative lactonization of 1,6- and 1,7-diols, directly affording seven- and eight-membered lactones, respectively, in good yields.

    Original languageEnglish
    Pages (from-to)39-42
    Number of pages4
    JournalOrganic and Biomolecular Chemistry
    Volume8
    Issue number1
    DOIs
    Publication statusPublished - 2010

    ASJC Scopus subject areas

    • Biochemistry
    • Physical and Theoretical Chemistry
    • Organic Chemistry

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