Highly efficient encapsulation of ingredients in poly(methyl methacrylate) capsules using a superoleophobic material

Takayuki Takei, Kiyotaka Araki, Keita Terazono, Yoshihiro Ozuno, Gen Hayase, Kazuyoshi Kanamori, Kazuki Nakanishi, Masahiro Yoshida

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Increasing the efficiency of encapsulation of ingredients into spherical capsules can decrease the manufacturing costs of the capsules. Ingredients can be encapsulated with high efficiency (>99%) into nondegradable hard resin capsules prepared by polymerization of spherical droplets of trimethylolpropane trimethacrylate (TRIM) monomer placed on a superoleophobic material. Poly(methyl methacrylate) (PMMA) resin is a more versatile capsule material than poly-TRIM resin. In this study, the efficiency of encapsulation in PMMA resin capsules prepared from methyl methacrylate (MMA) monomer was investigated. To reduce the volatility of the MMA monomer, pre-polymerized MMA was used for capsule preparation. Although non-volatile α-tocopherol and doxorubicin could be encapsulated in the capsules with high efficiency by heat polymerization at 60°C for 3 h, the efficiency for volatile tetradecane was much lower (approximately 60%) because it evaporated. Furthermore, even when using pre-polymerized MMA, more than 70% of the prepolymer evaporated during polymerization. To prevent the evaporation of tetradecane and the prepolymer, ultraviolet photopolymerization was adopted because it was faster and could be conducted at a lower temperature. The photopolymerization prevented the evaporation of the prepolymer and increased the efficiency of encapsulation of tetradecane (approximately 90% efficiency). This polymerization system is effective for encapsulation of ingredients in PMMA capsules with high efficiency.

Original languageEnglish
Pages (from-to)129-134
Number of pages6
JournalPolymers and Polymer Composites
Issue number2
Publication statusPublished - 2017 Feb

ASJC Scopus subject areas

  • Ceramics and Composites
  • Polymers and Plastics
  • Materials Chemistry


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