Taking shortcuts: A remarkably short and high-yielding asymmetric total synthesis of (-)-oseltamivir takes advantage of organocatalysis and single-pot domino operations. The target, known as the drug Tamiflu, is prepared efficiently in a short time, and also its derivatives can be synthesized effectively.
|Number of pages||4|
|Journal||Angewandte Chemie - International Edition|
|Publication status||Published - 2009 Feb 2|
- Antiviral agents
- Domino reactions
ASJC Scopus subject areas