Abstract
Solid-phase syntheses of combinatorial libraries based on natural products, such as, (i) vitamin D3, (ii) macrosphelide A, (iii) aurilide, (iv) aeruginosin 298-A, (v) trisaccharides, (vi) clavulone, (vii) 15-deoxyPGJ 2, (viii) phlorizin, (ix) naltrindole, and (x) norbinaltorphimine are described. The highly convergent synthetic strategies that enable the high-throughput syntheses of their derivatives are also outlined.
Original language | English |
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Pages (from-to) | 795-804 |
Number of pages | 10 |
Journal | Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry |
Volume | 65 |
Issue number | 8 |
DOIs | |
Publication status | Published - 2007 Aug |
Externally published | Yes |
Keywords
- Alkaloids
- Combinatorial synthesis
- Natural products
- Oligosaccharides
- Peptides
- Solid-phase synthesis
- Split & mix method
- Steroids
- Terpenes
ASJC Scopus subject areas
- Organic Chemistry