Abstract
Solid-phase syntheses of combinatorial libraries based on natural products, such as, (i) vitamin D3, (ii) macrosphelide A, (iii) aurilide, (iv) aeruginosin 298-A, (v) trisaccharides, (vi) clavulone, (vii) 15-deoxyPGJ 2, (viii) phlorizin, (ix) naltrindole, and (x) norbinaltorphimine are described. The highly convergent synthetic strategies that enable the high-throughput syntheses of their derivatives are also outlined.
| Original language | English |
|---|---|
| Pages (from-to) | 795-804 |
| Number of pages | 10 |
| Journal | Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry |
| Volume | 65 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2007 Aug |
| Externally published | Yes |
Keywords
- Alkaloids
- Combinatorial synthesis
- Natural products
- Oligosaccharides
- Peptides
- Solid-phase synthesis
- Split & mix method
- Steroids
- Terpenes
ASJC Scopus subject areas
- Organic Chemistry
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Cite this
Doi, T., Tanaka, H., & Takahashi, T. (2007). High-throughput synthesis of combinatorial libraries based on natural products. Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 65(8), 795-804. https://doi.org/10.5059/yukigoseikyokaishi.65.795