High-throughput synthesis of combinatorial libraries based on natural products

Takayuki Doi; Hiroshi Tanaka; Takashi Takahashi

doi:10.5059/yukigoseikyokaishi.65.795

High-throughput synthesis of combinatorial libraries based on natural products

Takayuki Doi, Hiroshi Tanaka, Takashi Takahashi

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Solid-phase syntheses of combinatorial libraries based on natural products, such as, (i) vitamin D₃, (ii) macrosphelide A, (iii) aurilide, (iv) aeruginosin 298-A, (v) trisaccharides, (vi) clavulone, (vii) 15-deoxyPGJ ₂, (viii) phlorizin, (ix) naltrindole, and (x) norbinaltorphimine are described. The highly convergent synthetic strategies that enable the high-throughput syntheses of their derivatives are also outlined.

Original language	English
Pages (from-to)	795-804
Number of pages	10
Journal	Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Volume	65
Issue number	8
DOIs	https://doi.org/10.5059/yukigoseikyokaishi.65.795
Publication status	Published - 2007 Aug
Externally published	Yes

Keywords

Alkaloids
Combinatorial synthesis
Natural products
Oligosaccharides
Peptides
Solid-phase synthesis
Split & mix method
Steroids
Terpenes

ASJC Scopus subject areas

Organic Chemistry

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title = "High-throughput synthesis of combinatorial libraries based on natural products",

abstract = "Solid-phase syntheses of combinatorial libraries based on natural products, such as, (i) vitamin D3, (ii) macrosphelide A, (iii) aurilide, (iv) aeruginosin 298-A, (v) trisaccharides, (vi) clavulone, (vii) 15-deoxyPGJ 2, (viii) phlorizin, (ix) naltrindole, and (x) norbinaltorphimine are described. The highly convergent synthetic strategies that enable the high-throughput syntheses of their derivatives are also outlined.",

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AU - Tanaka, Hiroshi

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KW - Peptides

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KW - Steroids

KW - Terpenes

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High-throughput synthesis of combinatorial libraries based on natural products

Abstract

Keywords

ASJC Scopus subject areas

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