High-throughput coagulation by heating with laterally enlarged focus, enhanced by mircobubble clouds created by electronically scanned trigger pulses

Shinichiro Umemura, Yuta Inaba, Tatsuya Moriyama, Jumpei Okada, Shin Yoshizawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Microbubbles are known to enhance ultrasonic tissue heating. However, they do not always provide the desired temperature distribution for high-intensity focused ultrasound (HIFU) treatment unless they are localized in the tissue to be treated. Cavitation clouds, locally generated by extremely high intensity short pulses, can enhance the effect of immediately following heating waves. The throughput of HIFU treatment may significantly be improved thereby. The treatment throughput may be improved even further when generation of multiple cavitation clouds by fast electronic scanning is combined with heating waves with an enlarged focus. The bio-heat transfer simulation showed that heating with an enlarged focus showed higher treatment efficiency than a single spot focus even without trigger pulses generating cavitation clouds, but higher acoustic power is needed. When the heating with an enlarged focus immediately followed the electronically scanned trigger pulses with multiple foci, it showed higher treatment efficiency even at low acoustic power.

Original languageEnglish
Title of host publication2011 IEEE International Ultrasonics Symposium, IUS 2011
Pages120-123
Number of pages4
DOIs
Publication statusPublished - 2011 Dec 1
Event2011 IEEE International Ultrasonics Symposium, IUS 2011 - Orlando, FL, United States
Duration: 2011 Oct 182011 Oct 21

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Other

Other2011 IEEE International Ultrasonics Symposium, IUS 2011
CountryUnited States
CityOrlando, FL
Period11/10/1811/10/21

Keywords

  • HIFU
  • cavitation cloud
  • enlarged focus
  • microbubbles

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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    Umemura, S., Inaba, Y., Moriyama, T., Okada, J., & Yoshizawa, S. (2011). High-throughput coagulation by heating with laterally enlarged focus, enhanced by mircobubble clouds created by electronically scanned trigger pulses. In 2011 IEEE International Ultrasonics Symposium, IUS 2011 (pp. 120-123). [6293555] (IEEE International Ultrasonics Symposium, IUS). https://doi.org/10.1109/ULTSYM.2011.0030