TY - GEN
T1 - High-throughput coagulation by heating with laterally enlarged focus, enhanced by mircobubble clouds created by electronically scanned trigger pulses
AU - Umemura, Shinichiro
AU - Inaba, Yuta
AU - Moriyama, Tatsuya
AU - Okada, Jumpei
AU - Yoshizawa, Shin
PY - 2011/12/1
Y1 - 2011/12/1
N2 - Microbubbles are known to enhance ultrasonic tissue heating. However, they do not always provide the desired temperature distribution for high-intensity focused ultrasound (HIFU) treatment unless they are localized in the tissue to be treated. Cavitation clouds, locally generated by extremely high intensity short pulses, can enhance the effect of immediately following heating waves. The throughput of HIFU treatment may significantly be improved thereby. The treatment throughput may be improved even further when generation of multiple cavitation clouds by fast electronic scanning is combined with heating waves with an enlarged focus. The bio-heat transfer simulation showed that heating with an enlarged focus showed higher treatment efficiency than a single spot focus even without trigger pulses generating cavitation clouds, but higher acoustic power is needed. When the heating with an enlarged focus immediately followed the electronically scanned trigger pulses with multiple foci, it showed higher treatment efficiency even at low acoustic power.
AB - Microbubbles are known to enhance ultrasonic tissue heating. However, they do not always provide the desired temperature distribution for high-intensity focused ultrasound (HIFU) treatment unless they are localized in the tissue to be treated. Cavitation clouds, locally generated by extremely high intensity short pulses, can enhance the effect of immediately following heating waves. The throughput of HIFU treatment may significantly be improved thereby. The treatment throughput may be improved even further when generation of multiple cavitation clouds by fast electronic scanning is combined with heating waves with an enlarged focus. The bio-heat transfer simulation showed that heating with an enlarged focus showed higher treatment efficiency than a single spot focus even without trigger pulses generating cavitation clouds, but higher acoustic power is needed. When the heating with an enlarged focus immediately followed the electronically scanned trigger pulses with multiple foci, it showed higher treatment efficiency even at low acoustic power.
KW - HIFU
KW - cavitation cloud
KW - enlarged focus
KW - microbubbles
UR - http://www.scopus.com/inward/record.url?scp=84869010015&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84869010015&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2011.0030
DO - 10.1109/ULTSYM.2011.0030
M3 - Conference contribution
AN - SCOPUS:84869010015
SN - 9781457712531
T3 - IEEE International Ultrasonics Symposium, IUS
SP - 120
EP - 123
BT - 2011 IEEE International Ultrasonics Symposium, IUS 2011
T2 - 2011 IEEE International Ultrasonics Symposium, IUS 2011
Y2 - 18 October 2011 through 21 October 2011
ER -