High-risk area of hemolysis in the helical flow pump for total artificial heart

Kohei Ishii; Fumiya Katsuura; Akira Heya; Xinyang Li; Takashi Isoyama; Itsuro Saito; Yusuke Inoue; Masami Sato; Shintaro Hara; Sheng Yuan Wu; Hidemoto Nakagawa; Toshiya Ono; Kou Imachi; Yusuke Abe

doi:10.11239/jsmbe.52.O-535

High-risk area of hemolysis in the helical flow pump for total artificial heart

Kohei Ishii, Fumiya Katsuura, Akira Heya, Xinyang Li, Takashi Isoyama, Itsuro Saito, Yusuke Inoue, Masami Sato, Shintaro Hara, Sheng Yuan Wu, Hidemoto Nakagawa, Toshiya Ono, Kou Imachi, Yusuke Abe

PreClinical Research Center

Research output: Contribution to journal › Article › peer-review

Abstract

The helical flow pump (HFP) for the total artificial heart (TAH) has been developed. In the recent hemolysis test, normalized index of hemolysis (NIH) of HFP is 0.71 times of BioPump (BPX-80). Comparing to blood pumps in clinical field, further improvement is still significant task. Computational fluid dynamics analysis is carried out to determine risky area of the hemolysis in the flow passage except hydrodynamic bearing. And shear stress and duration along the stream lines which is regarded as a path of Red blood cells are analyzed. As the result, 0 deg and 180 deg of rotational angle where confluent or split-flow with large flow speed difference are clarified as risky area of hemolysis.

Original language	English
Pages (from-to)	O-535-O-536
Journal	Transactions of Japanese Society for Medical and Biological Engineering
Volume	52
DOIs	https://doi.org/10.11239/jsmbe.52.O-535
Publication status	Published - 2014 Aug 17

Keywords

Helical flow pump
Hemolysis
Total artificial heart

ASJC Scopus subject areas

Biomedical Engineering

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10.11239/jsmbe.52.O-535

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Ishii, K., Katsuura, F., Heya, A., Li, X., Isoyama, T., Saito, I., Inoue, Y., Sato, M., Hara, S., Wu, S. Y., Nakagawa, H., Ono, T., Imachi, K., & Abe, Y. (2014). High-risk area of hemolysis in the helical flow pump for total artificial heart. Transactions of Japanese Society for Medical and Biological Engineering, 52, O-535-O-536. https://doi.org/10.11239/jsmbe.52.O-535

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title = "High-risk area of hemolysis in the helical flow pump for total artificial heart",

abstract = "The helical flow pump (HFP) for the total artificial heart (TAH) has been developed. In the recent hemolysis test, normalized index of hemolysis (NIH) of HFP is 0.71 times of BioPump (BPX-80). Comparing to blood pumps in clinical field, further improvement is still significant task. Computational fluid dynamics analysis is carried out to determine risky area of the hemolysis in the flow passage except hydrodynamic bearing. And shear stress and duration along the stream lines which is regarded as a path of Red blood cells are analyzed. As the result, 0 deg and 180 deg of rotational angle where confluent or split-flow with large flow speed difference are clarified as risky area of hemolysis.",

keywords = "Helical flow pump, Hemolysis, Total artificial heart",

author = "Kohei Ishii and Fumiya Katsuura and Akira Heya and Xinyang Li and Takashi Isoyama and Itsuro Saito and Yusuke Inoue and Masami Sato and Shintaro Hara and Wu, {Sheng Yuan} and Hidemoto Nakagawa and Toshiya Ono and Kou Imachi and Yusuke Abe",

year = "2014",

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doi = "10.11239/jsmbe.52.O-535",

language = "English",

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T1 - High-risk area of hemolysis in the helical flow pump for total artificial heart

AU - Ishii, Kohei

AU - Katsuura, Fumiya

AU - Heya, Akira

AU - Li, Xinyang

AU - Isoyama, Takashi

AU - Saito, Itsuro

AU - Inoue, Yusuke

AU - Sato, Masami

AU - Hara, Shintaro

AU - Wu, Sheng Yuan

AU - Nakagawa, Hidemoto

AU - Ono, Toshiya

AU - Imachi, Kou

AU - Abe, Yusuke

PY - 2014/8/17

Y1 - 2014/8/17

N2 - The helical flow pump (HFP) for the total artificial heart (TAH) has been developed. In the recent hemolysis test, normalized index of hemolysis (NIH) of HFP is 0.71 times of BioPump (BPX-80). Comparing to blood pumps in clinical field, further improvement is still significant task. Computational fluid dynamics analysis is carried out to determine risky area of the hemolysis in the flow passage except hydrodynamic bearing. And shear stress and duration along the stream lines which is regarded as a path of Red blood cells are analyzed. As the result, 0 deg and 180 deg of rotational angle where confluent or split-flow with large flow speed difference are clarified as risky area of hemolysis.

AB - The helical flow pump (HFP) for the total artificial heart (TAH) has been developed. In the recent hemolysis test, normalized index of hemolysis (NIH) of HFP is 0.71 times of BioPump (BPX-80). Comparing to blood pumps in clinical field, further improvement is still significant task. Computational fluid dynamics analysis is carried out to determine risky area of the hemolysis in the flow passage except hydrodynamic bearing. And shear stress and duration along the stream lines which is regarded as a path of Red blood cells are analyzed. As the result, 0 deg and 180 deg of rotational angle where confluent or split-flow with large flow speed difference are clarified as risky area of hemolysis.

KW - Helical flow pump

KW - Hemolysis

KW - Total artificial heart

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JO - BME = Bio medical engineering / henshu, Nihon ME Gakkai

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ER -

High-risk area of hemolysis in the helical flow pump for total artificial heart

Abstract

Keywords

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