TY - JOUR
T1 - High prevalence of diffuse large B-cell lymphoma in occult hepatitis B virus-infected patients in the Tohoku district in Eastern Japan
AU - for the Tohoku Hematology Forum
AU - Tajima, Katsushi
AU - Takahashi, Naoto
AU - Ishizawa, Kenichi
AU - Murai, Kazunori
AU - Akagi, Tomoaki
AU - Noji, Hideyoshi
AU - Sasaki, Osamu
AU - Wano, Masaharu
AU - Itoh, Jugoh
AU - Kato, Yuichi
AU - Scichishima, Tsutomu
AU - Ishida, Yoji
AU - Harigae, Hideo
AU - Sawada, Kenichi
N1 - Publisher Copyright:
© 2016 Wiley Periodicals, Inc.
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Occult hepatitis B virus (HBV) infection is a clinical challenge, but its relationship to clinicopathologic features and the risk of progression to malignant lymphoma (ML) are poorly defined. We estimated the prevalence of HBV infection of 1,358 patients with newly diagnosed ML. HBV infection was more prevalent in ML than in control patients. The occult HBV infection group had a higher median onset age, no liver or spleen involvement, and higher prevalence of diffuse large B-cell lymphoma than the other groups, indicating that occult HBV infection is a distinct clinicopathologic entity. J. Med. Virol. 88:2206–2210, 2016.
AB - Occult hepatitis B virus (HBV) infection is a clinical challenge, but its relationship to clinicopathologic features and the risk of progression to malignant lymphoma (ML) are poorly defined. We estimated the prevalence of HBV infection of 1,358 patients with newly diagnosed ML. HBV infection was more prevalent in ML than in control patients. The occult HBV infection group had a higher median onset age, no liver or spleen involvement, and higher prevalence of diffuse large B-cell lymphoma than the other groups, indicating that occult HBV infection is a distinct clinicopathologic entity. J. Med. Virol. 88:2206–2210, 2016.
KW - clinicopathologic features
KW - diffuse large B-cell lymphoma
KW - hepatitis B virus
KW - malignant lymphoma
KW - occult HBV infection
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U2 - 10.1002/jmv.24584
DO - 10.1002/jmv.24584
M3 - Article
C2 - 27219865
AN - SCOPUS:84989947082
VL - 88
SP - 2206
EP - 2210
JO - Journal of Medical Virology
JF - Journal of Medical Virology
SN - 0146-6615
IS - 12
ER -