High prevalence of diffuse large B-cell lymphoma in occult hepatitis B virus-infected patients in the Tohoku district in Eastern Japan

for the Tohoku Hematology Forum

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Occult hepatitis B virus (HBV) infection is a clinical challenge, but its relationship to clinicopathologic features and the risk of progression to malignant lymphoma (ML) are poorly defined. We estimated the prevalence of HBV infection of 1,358 patients with newly diagnosed ML. HBV infection was more prevalent in ML than in control patients. The occult HBV infection group had a higher median onset age, no liver or spleen involvement, and higher prevalence of diffuse large B-cell lymphoma than the other groups, indicating that occult HBV infection is a distinct clinicopathologic entity. J. Med. Virol. 88:2206–2210, 2016.

Original languageEnglish
Pages (from-to)2206-2210
Number of pages5
JournalJournal of Medical Virology
Volume88
Issue number12
DOIs
Publication statusPublished - 2016 Dec 1

Keywords

  • clinicopathologic features
  • diffuse large B-cell lymphoma
  • hepatitis B virus
  • malignant lymphoma
  • occult HBV infection

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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