High pressure mediated Diels-Alder reaction using 2-iminomalonates as dienophiles: novel synthesis of carbocyclic nucleosides.

N. Katagiri; A. Kurimoto; K. Kitano; H. Nochi; H. Sato; C. Kaneko

High pressure mediated Diels-Alder reaction using 2-iminomalonates as dienophiles: novel synthesis of carbocyclic nucleosides.

N. Katagiri, A. Kurimoto, K. Kitano, H. Nochi, H. Sato, C. Kaneko

PHA - Pharmacy

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

9-[c-4-(1,2-Dihydroxyethyl)cyclopent-2-en-r-1-yl]-9H-adenine , an isomer of BCA, has been synthesized from Diels-Alder adducts prepared by the reaction of 2-iminomalonates with cyclopentadiene under high pressure. The synthetic method involves a novel C-N bond cleavage reaction by NaBH4-K2CO3 (RRA reaction conditions) and has wide applicability for the synthesis of various carbocyclic nucleosides.

Original language	English
Pages (from-to)	83-84
Number of pages	2
Journal	Nucleic acids symposium series
Issue number	27
Publication status	Published - 1992

ASJC Scopus subject areas

Medicine(all)

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title = "High pressure mediated Diels-Alder reaction using 2-iminomalonates as dienophiles: novel synthesis of carbocyclic nucleosides.",

abstract = "9-[c-4-(1,2-Dihydroxyethyl)cyclopent-2-en-r-1-yl]-9H-adenine , an isomer of BCA, has been synthesized from Diels-Alder adducts prepared by the reaction of 2-iminomalonates with cyclopentadiene under high pressure. The synthetic method involves a novel C-N bond cleavage reaction by NaBH4-K2CO3 (RRA reaction conditions) and has wide applicability for the synthesis of various carbocyclic nucleosides.",

author = "N. Katagiri and A. Kurimoto and K. Kitano and H. Nochi and H. Sato and C. Kaneko",

year = "1992",

language = "English",

pages = "83--84",

journal = "Nucleic acids symposium series",

issn = "0261-3166",

publisher = "Information Retrieval",

number = "27",

}

TY - JOUR

T1 - High pressure mediated Diels-Alder reaction using 2-iminomalonates as dienophiles

T2 - novel synthesis of carbocyclic nucleosides.

AU - Katagiri, N.

AU - Kurimoto, A.

AU - Kitano, K.

AU - Nochi, H.

AU - Sato, H.

AU - Kaneko, C.

PY - 1992

Y1 - 1992

N2 - 9-[c-4-(1,2-Dihydroxyethyl)cyclopent-2-en-r-1-yl]-9H-adenine , an isomer of BCA, has been synthesized from Diels-Alder adducts prepared by the reaction of 2-iminomalonates with cyclopentadiene under high pressure. The synthetic method involves a novel C-N bond cleavage reaction by NaBH4-K2CO3 (RRA reaction conditions) and has wide applicability for the synthesis of various carbocyclic nucleosides.

AB - 9-[c-4-(1,2-Dihydroxyethyl)cyclopent-2-en-r-1-yl]-9H-adenine , an isomer of BCA, has been synthesized from Diels-Alder adducts prepared by the reaction of 2-iminomalonates with cyclopentadiene under high pressure. The synthetic method involves a novel C-N bond cleavage reaction by NaBH4-K2CO3 (RRA reaction conditions) and has wide applicability for the synthesis of various carbocyclic nucleosides.

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M3 - Article

C2 - 1289835

AN - SCOPUS:0027034230

SP - 83

EP - 84

JO - Nucleic acids symposium series

JF - Nucleic acids symposium series

SN - 0261-3166

IS - 27

ER -