Abstract
9-[c-4-(1,2-Dihydroxyethyl)cyclopent-2-en-r-1-yl]-9H-adenine , an isomer of BCA, has been synthesized from Diels-Alder adducts prepared by the reaction of 2-iminomalonates with cyclopentadiene under high pressure. The synthetic method involves a novel C-N bond cleavage reaction by NaBH4-K2CO3 (RRA reaction conditions) and has wide applicability for the synthesis of various carbocyclic nucleosides.
Original language | English |
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Pages (from-to) | 83-84 |
Number of pages | 2 |
Journal | Nucleic acids symposium series |
Issue number | 27 |
Publication status | Published - 1992 |
ASJC Scopus subject areas
- Medicine(all)