High pressure in enzyme catalyzed organic reactions

Nobuya Katagiri, Masahiko Yamaguchi, Chikara Kaneko

Research output: Contribution to journalArticle

6 Citations (Scopus)


Adenosine deaminase and lipases catalyzed hydrolysis under high pressure were described. The hydrolysis by both enzymes was facilitated by high pressures. This technique was used for the kinetical resolution of racemic highly modified nucleosides having biological activities.

Original languageEnglish
Pages (from-to)1023-1043
Number of pages21
Issue number5
Publication statusPublished - 1998 Jan 1

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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    Katagiri, N., Yamaguchi, M., & Kaneko, C. (1998). High pressure in enzyme catalyzed organic reactions. Heterocycles, 48(5), 1023-1043. https://doi.org/10.3987/REV-98-496