High pressure in enzyme catalyzed organic reactions

Nobuya Katagiri; Masahiko Yamaguchi; Chikara Kaneko

doi:10.3987/REV-98-496

High pressure in enzyme catalyzed organic reactions

Nobuya Katagiri, Masahiko Yamaguchi, Chikara Kaneko

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Adenosine deaminase and lipases catalyzed hydrolysis under high pressure were described. The hydrolysis by both enzymes was facilitated by high pressures. This technique was used for the kinetical resolution of racemic highly modified nucleosides having biological activities.

Original language	English
Pages (from-to)	1023-1043
Number of pages	21
Journal	Heterocycles
Volume	48
Issue number	5
DOIs	https://doi.org/10.3987/REV-98-496
Publication status	Published - 1998 Jan 1

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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title = "High pressure in enzyme catalyzed organic reactions",

abstract = "Adenosine deaminase and lipases catalyzed hydrolysis under high pressure were described. The hydrolysis by both enzymes was facilitated by high pressures. This technique was used for the kinetical resolution of racemic highly modified nucleosides having biological activities.",

author = "Nobuya Katagiri and Masahiko Yamaguchi and Chikara Kaneko",

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AU - Katagiri, Nobuya

AU - Yamaguchi, Masahiko

AU - Kaneko, Chikara

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JO - Heterocycles

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High pressure in enzyme catalyzed organic reactions

Abstract

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