High Pressure Elicits Unexpected Transformations of Plain Nitroaromatics with 4-(Cyclohex-1-en-1-yl)morpholine

Sonia Diab, Ludovik Noël-Duchesneau, Morgane Sanselme, Yoshinori Kondo, Michael De Paolis, Isabelle Chataigner

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


An unexpected reaction sequence occurs when simple nitroarenes and the readily available enamine 4-(cyclohex-1-en-1-yl)morpholine are placed under high pressure. This one-pot transformation leads to the generation of highly substituted compounds and presents different advantages such as (1) a rapid increase of molecular complexity through converting simple, cheap, and seldom exploited starting materials into polycyclic structures never described before, (2) the absence of chemical catalysts, (3) a very low energy input.

Original languageEnglish
Pages (from-to)2048-2052
Number of pages5
JournalEuropean Journal of Organic Chemistry
Issue number18
Publication statusPublished - 2018 May 15


  • Amines
  • Heterocycles
  • High pressure
  • Nitroaromatic compounds

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry


Dive into the research topics of 'High Pressure Elicits Unexpected Transformations of Plain Nitroaromatics with 4-(Cyclohex-1-en-1-yl)morpholine'. Together they form a unique fingerprint.

Cite this