High b-value diffusion-weighted MRI for detecting gallbladder carcinoma: Preliminary study and results

Reiji Sugita, Tetsuro Yamazaki, Akemi Furuta, Kei Itoh, Naotaka Fujita, Shoki Takahashi

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43 Citations (Scopus)

Abstract

The aim of this preliminary study was to retrospectively evaluate the usefulness of high b-value diffusion-weighted MR imaging (DWI) in the detection of gallbladder carcinoma. Fifteen patients with gallbladder carcinoma and 14 other patients were included in this study. All patients and subjects underwent DWI, and images were evaluated by two radiologists. The area under the receiver operating characteristic curve (AUC), apparent diffusion coefficient (ADC) measurement, sensitivity and specificity were calculated. An AUC yielded 0.980 (95% CI, 0.850-0.999) and 0.941 (95% CI, 0.791-0.990) for the two radiologists. The mean sensitivity and specificity were 83.3% and 100%, respectively. The mean ADC value of gallbladder carcinoma was (1.28±0.41)×10-3 mm2/s and that of control gallbladder lesions was (1.92±0.21)×10-3 mm2/s (P<0.01). According to the results of our preliminary study, high b-value DWI might be a useful tool for detecting gallbladder carcinoma by measuring the ADC value and direct visual assessment.

Original languageEnglish
Pages (from-to)1794-1798
Number of pages5
JournalEuropean Radiology
Volume19
Issue number7
DOIs
Publication statusPublished - 2009

Keywords

  • Diffusion
  • Gallbladder carcinoma
  • MRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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