Hg2+-trapping beads: Hg2+-specific recognition through thymine-Hg(II)-thymine base pairing

Mituhiro Kuriyama, Kaichiro Haruta, Takenori Dairaku, Takuya Kawamura, Shoko Kikkawa, Kiyofumi Inamoto, Hirokazu Tsukamoto, Yoshinori Kondo, Hidetaka Torigoe, Itaru Okamoto, Akira Ono, Eugene Hayato Morita, Yoshiyuki Tanaka

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Mercury pollution poses a severe threat to human health. To remove Hg 2+ from contaminated water, we synthesized Hg2+-trapping beads that include oligo-thymidine functionalities that can form thymine-Hg(II)-thymine base pairs on the solid support. The beads can selectively trap Hg2+ even in the presence of other metal cations. More interestingly, Hg2+-trapping efficiency was higher in the presence of the co-existing cations. Thus, the developed Hg2+- trapping beads can capture Hg2+ without affecting the mineral balance of water so much. The Hg2+-trapping beads presented here show promise for removing Hg2+ from environmental water.

Original languageEnglish
Pages (from-to)709-712
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Issue number7
Publication statusPublished - 2014 Jul


  • DNA-metal interaction
  • Mercury removal
  • Oligonucleotide
  • Thymine
  • Thymine-Hg(II)-thymine base pair

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery


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