Hepatic clearance of 99mTc-GSA in cases of postoperative biliary atresia -a retrospective comparison with hepatic clearance of 99mTc-PMT-

Tetsuro Yamazaki, Shin Maruoka, Shogo Yamada

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1 Citation (Scopus)

Abstract

There are a few reports about usefulness of 99mTcGSA liver scintigraphy (GSA imaging) for the evaluation of postoperative state of biliary atresia. However, comparison of significance for the disease between GSA imaging and 99mTc-PMT hepatobiliary imaging have not been reported. Fifty-six GSA imagings for 41 postoperative biliary atresia patients were reviewed and their scintigraphic findings and the functional parameters were compared with those obtained from 99mTc-PMT hepatobiliary imaging. In quantitative analysis, although the hepatic clearance of both tracers calculated by graphical analysis (Patlak plot) were well correlated in most cases, a discrepancy was observed in several cases with jaundice. The authors conclude that the hepatic clearance of 99mTc-GSA is a more accurate index of the hepatic reserve than that of 99mTc-PMT which can be influenced by hyperbilirubinemia and that the combination of both examinations is helpful to evaluate development of liver injury in postoperative biliary atresia patients.

Original languageEnglish
Pages (from-to)855-856
Number of pages2
JournalKakuigaku
Volume35
Issue number9
Publication statusPublished - 1998 Dec 1

Keywords

  • Asialoglycoprotein receptor imaging
  • Biliary atresia
  • Hepatobiliary scintigraphy
  • Liver function

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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