Hemorrhagic onset of pilocytic astrocytoma and pilomyxoid astrocytoma

Ichiyo Shibahara, Masayuki Kanamori, Toshihiro Kumabe, Hidenori Endo, Yukihiko Sonoda, Yoshikazu Ogawa, Mika Watanabe, Teiji Tominaga

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The incidence of hemorrhagic onset in pilocytic astrocytoma and pilomyxoid astrocytoma, and the clinical and histological characteristics, were compared to other types of neuroepithelial tumors or nonhemorrhagic pilocytic astrocytoma by retrospective review of 445 consecutive neuroepithelial tumors treated at our institute. Hemorrhagic onset was observed in 4 of 35 (11.4%) patients with pilocytic astrocytoma and pilomyxoid astrocytoma, with higher incidence than in glioblastoma (3.9%), anaplastic oligodendroglioma (7.7%), and anaplastic ependymoma (7.1%). The hemorrhagic onset occurred in 2 patients with sporadic pilocytic astrocytoma, 1 with pilocytic astrocytoma associated with neurofibromatosis type 1, and 1 with pilomyxoid astrocytoma. There was no correlation between hemorrhagic onset and clinical features, including age, sex, tumor location, proliferative activity, or microvascular proliferation. Hemorrhagic onset of pilocytic astrocytoma and pilomyxoid astrocytoma is not as uncommon as was previously thought, so pilocytic astrocytoma or pilomyxoid astrocytoma should be considered in the differential diagnosis of patients with brain tumors manifesting as hemorrhagic onset.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalBrain Tumor Pathology
Volume26
Issue number1
DOIs
Publication statusPublished - 2009 Apr

Keywords

  • Hemorrhagic onset
  • Pilocytic astrocytoma
  • Pilomyxoid astrocytoma

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology
  • Cancer Research

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