Hair growth regulation by the extract of aromatic plant Erica multiflora

Mitsuko Kawano, Junkyu Han, Mohamed Elyes Kchouk, Hiroko Isoda

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Hair growth problems can affect human physical and mental health and are of particular relevance during the aging process. In an effort to resolve such problems, we attempted to find plants having hair growth regulation activity and thus collected plant extracts from Tunisia for bioprospecting purposes. Among them, we investigated the Erica multiflora extract to evaluate the hair growth promotion activity by using the MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl- 2H-tetrazolium bromide) assay and cell cycle assay on human dermal papilla cells in vitro and an administration assay on mouse dorsal skin in vivo. The results showed that the Erica multiflora extract promotes dermal papilla cell growth and cell cycle with high activity, and induced hair growth in vivo by induction of anagen phase from telogen phase.

Original languageEnglish
Pages (from-to)335-339
Number of pages5
JournalJournal of Natural Medicines
Issue number3
Publication statusPublished - 2009 Jul


  • Anagen induction
  • Dermal papilla
  • Erica multiflora
  • Hair growth cycle
  • Vasodilatation

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


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