Haemophilus influenzae has a GM1 ganglioside-like structure and elicits Guillain-Barre syndrome

Masahiro Mori, S. Kuwabara, M. Miyake, M. Dezawa, E. Adachi-Usami, H. Kuroki, M. Noda, T. Hattori

Research output: Contribution to journalArticlepeer-review

60 Citations (Scopus)

Abstract

The authors report a patient with an axonal Guillain-Barre syndrome (acute motor axonal neuropathy) associated with anti-GM1 antibody after Haemophilus influenzae infection. The result of ELISA inhibition studies and cytochemical staining with cholera toxin suggest the presence of a GM1-like structure on the surface of H. influenzae isolated from the patient. A particular strain of H. influenzae may have a GM1-like structure and may elicit an axonal Guillain-Barre syndrome.

Original languageEnglish
Pages (from-to)1282-1284
Number of pages3
JournalNeurology
Volume52
Issue number6
DOIs
Publication statusPublished - 1999 Apr 12
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

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