TY - JOUR
T1 - Gustatory and visceral inputs to the amygdala of the rat
T2 - Conditioned taste aversion and induction of c-fos-like immunoreactivity
AU - Yamamoto, Takashi
AU - Sako, Noritaka
AU - Sakai, Nobuyuki
AU - Iwafune, Akiko
N1 - Funding Information:
This work was supported by Grants-in-Aid for Scientific Research (Nos. 07457438 and 08877275) from the Ministry of Education, Science, Sports and Culture of Japan.
PY - 1997/4/25
Y1 - 1997/4/25
N2 - Expression of proto-oncogene c-fos was immunohistochemically examined in the central and basolateral amygdaloid nuclei in rats after ingestion of taste solutions (0.5 M sucrose or 0.005 M saccharin), intragastric infusion of these solutions, or an intraperitoneal injection of malaise-inducing lithium chloride (LiCl). C-Fos-like immunoreactive neurons were distributed most densely in the central nucleus in response to the LiCl injection, followed by the ingestion and intragastric infusion of sucrose. The intraoral infusion of sucrose, but not of saccharin, elicited intense c-fos expression in the central nucleus after establishment of conditioned taste aversion to these taste stimuli. The results are discussed in terms of post-ingestional factors and the conditioned illness reaction after taste aversion learning.
AB - Expression of proto-oncogene c-fos was immunohistochemically examined in the central and basolateral amygdaloid nuclei in rats after ingestion of taste solutions (0.5 M sucrose or 0.005 M saccharin), intragastric infusion of these solutions, or an intraperitoneal injection of malaise-inducing lithium chloride (LiCl). C-Fos-like immunoreactive neurons were distributed most densely in the central nucleus in response to the LiCl injection, followed by the ingestion and intragastric infusion of sucrose. The intraoral infusion of sucrose, but not of saccharin, elicited intense c-fos expression in the central nucleus after establishment of conditioned taste aversion to these taste stimuli. The results are discussed in terms of post-ingestional factors and the conditioned illness reaction after taste aversion learning.
KW - Amygdala
KW - C-fos
KW - Conditioned taste aversion
KW - Immunohistochemistry
KW - Lithium chloride
KW - Taste
KW - Visceral sense
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U2 - 10.1016/S0304-3940(97)00265-6
DO - 10.1016/S0304-3940(97)00265-6
M3 - Article
C2 - 9159506
AN - SCOPUS:0030968279
VL - 226
SP - 127
EP - 130
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
IS - 2
ER -