Gorham disease of the spine: A case report and treatment strategies for this enigmatic bone disease

Toshimi Aizawa, Tetsuro Sato, Shoichi Kokubun

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Gorham disease is an extremely rare condition of unknown etiology characterized by progressive osteolysis. Only 28 cases of its spinal involvement have been reported, and some of those cases showed kyphosis, kyphoscoliosis, subluxation or dislocation. No definite regimen of treatment has been established yet. A 10-year-old boy presented with a severe and progressive kyphosis over 90 degrees caused by Gorham disease from T3 to T12. In situ posterior fusion with a hook and rod system and iliac bone grafts were performed, but after surgery, he had complete paraplegia and its cause was uncertain. Based on the unfortunate consequence of the present case and the review of the literature, we propose the treatment strategies for spinal Gorham disease.

Original languageEnglish
Pages (from-to)187-196
Number of pages10
JournalTohoku Journal of Experimental Medicine
Volume205
Issue number2
DOIs
Publication statusPublished - 2005 Feb

Keywords

  • Gorham disease
  • Kyphosis
  • Massive osteolysis
  • Spine
  • Surgical treatment

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Gorham disease of the spine: A case report and treatment strategies for this enigmatic bone disease'. Together they form a unique fingerprint.

Cite this