Abstract
Treatment of ortho-alkynylbenzoic acid esters with excess amounts of EtOH in the presence of a gold catalyst results in the liberation of alcohols or phenols in high yields under mild conditions. The protection of alcohols and phenols proceeds smoothly by use of ortho-alkynylbenzoic acid or ortho-iodobenzoyl chloride. Highly chemoselective deprotections are described.
Original language | English |
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Pages (from-to) | 7046-7049 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 49 |
Issue number | 49 |
DOIs | |
Publication status | Published - 2008 Dec 1 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry