Glycated albumin is not significantly correlated with body mass index in patients with acute-onset type 1 diabetes

Takumi Hirata, Masafumi Koga, Soji Kasayama, Jiro Morimoto, Taro Maruyama

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: No previous reports have clarified the relationship between glycated albumin (GA) and BMI in patients with acute-onset type 1 diabetes. Methods: We conducted a cross-sectional study evaluating the correlation between GA and BMI in 209 patients with acute-onset type 1 diabetes and in 159 patients with type 2 diabetes who were designated as the control group. The correlation between fasting serum C-peptide immunoreactivity (CPR) and GA or BMI was also evaluated to clarify the impact of insulin secretion capacity on the relationship between GA and BMI. Results: GA was significantly inversely correlated with BMI in patients with type 2 diabetes (r = -. 0.317, p. <. 0.001) but not in patients with type 1 diabetes (r = 0.031, p = NS). In patients with type 2 diabetes, GA was significantly inversely correlated with fasting CPR, and BMI was significantly correlated with fasting CPR. In patients with type 1 diabetes, GA was significantly inversely correlated with fasting CPR (r = -. 0.291, p. <. 0.001), but BMI was not correlated with fasting CPR (r = -. 0.010, p = NS). Conclusions: Unlike in patients with type 2 diabetes, GA was not significantly correlated with BMI in patients with acute-onset type 1 diabetes.

Original languageEnglish
Pages (from-to)248-251
Number of pages4
JournalClinica Chimica Acta
Volume438
DOIs
Publication statusPublished - 2015 Jan 1
Externally publishedYes

Keywords

  • Body mass index
  • C-peptide immunoreactivity
  • Glycated albumin
  • Glycated hemoglobin
  • Type 1 diabetes

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical

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