Glycanase-catalyzed synthesis of non-natural oligosaccharides

Shinichiro Shoda, M. Fujita, S. Kobayashi

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

A new methodology for the preparation of non-natural oligosaccharides has been developed using various glycosyl fluorides as activated glycosyl donors for enzymatic polycondensation. The reaction proceeds in a complete regio- and stereoselective manner to afford oligosaccharides of well-defined structures. The resulting oligosaccharides are difficult to prepare by conventional chemical methods with use of protecting groups.

Original languageEnglish
Pages (from-to)279-289
Number of pages11
JournalTrends in Glycoscience and Glycotechnology
Volume10
Issue number54
DOIs
Publication statusPublished - 1998 Jan 1

Keywords

  • Enzymatic glycosylation
  • Glycanase
  • Glycosyl fluoride
  • Non-natural oligosaccharide
  • Regio- and stereoselectivity

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Glycanase-catalyzed synthesis of non-natural oligosaccharides'. Together they form a unique fingerprint.

Cite this