Gibberellin metabolism and its regulation

Shinjiro Yamaguchi

    Research output: Contribution to journalReview article

    993 Citations (Scopus)

    Abstract

    Bioactive gibberellins (GAs) are diterpene plant hormones that are biosynthesized through complex pathways and control diverse aspects of growth and development. Biochemical, genetic, and genomic approaches have led to the identification of the majority of the genes that encode GA biosynthesis and deactivation enzymes. Recent studies have highlighted the occurrence of previously unrecognized deactivation mechanisms. It is now clear that both GA biosynthesis and deactivation pathways are tightly regulated by developmental, hormonal, and environmental signals, consistent with the role of GAs as key growth regulators. In some cases, the molecular mechanisms for fine-tuning the hormone levels are beginning to be uncovered. In this review, I summarize our current understanding of the GA biosynthesis and deactivation pathways in plants and fungi, and discuss how GA concentrations in plant tissues are regulated during development and in response to environmental stimuli.

    Original languageEnglish
    Pages (from-to)225-251
    Number of pages27
    JournalAnnual Review of Plant Biology
    Volume59
    DOIs
    Publication statusPublished - 2008 Jun 17

    Keywords

    • 2-oxoglutarate-dependent dioxygenase
    • Biosynthesis
    • Cytochrome P450 monooxygenase
    • Deactivation
    • Plant hormones
    • Terpene synthases

    ASJC Scopus subject areas

    • Physiology
    • Molecular Biology
    • Plant Science
    • Cell Biology

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