Abstract
Bat coronavirus (BtCoV) is assumed to be a progenitor of severe acute respiratory syndrome (SARS)-related coronaviruses. To explore the distribution of BtCoVs in the Philippines, we collected 179 bats and detected viral RNA from intestinal or fecal samples by RT-PCR. The overall prevalence of BtCoVs among bats was 29.6 %. Phylogenetic analysis of the partial RNA-dependent RNA polymerase gene suggested that one of the detected BtCoVs was a novel alphacoronavirus, while the others belonged to the genus Betacoronavirus. Western blotting revealed that 66.5 % of bat sera had antibodies to BtCoV. These surveys suggested the endemic presence of BtCoVs in the Philippines.
Original language | English |
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Pages (from-to) | 2349-2355 |
Number of pages | 7 |
Journal | Archives of virology |
Volume | 157 |
Issue number | 12 |
DOIs | |
Publication status | Published - 2012 Dec |
Keywords
- Antibody
- Bat coronavirus
- Bats
- Coronavirus
- SARS
- Severe acute respiratory syndrome
- Viruses
- Zoonosis
ASJC Scopus subject areas
- Virology