Generation of sub-nanosecond 586-nm optical pulses based on the synchronously gain-switched laser diodes with optical injection locking

Jui Hung Hung, Yuan Gao, Hejie Yan, Kazuo Sato, Hirohito Yamada, Lung Han Peng, Hiroyuki Yokoyama

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Stimulated emission depletion (STED) technology incorporated with fluorescence microscopy envisions biomedical samples to sub-diffraction-limit resolution. Pulsed-mode STED microscopy is attractive because milliwatt-level low average optical power can induce notable STED effect [1]. However, it is difficult to find stable and compact optical pulse sources that are suitable for STED. The pulsed operation of a laser diode (LD) can provide the stability and compactness, but the generated optical power is not very sufficient in general [2]. Therefore, we previously demonstrated a 1.3μm LD-based optical pulse source using an optical fiber amplifier (OFA) and second harmonic generation (SHG) to obtain high peak power (and thus high pulse energy) at 650nm band [3]. However, when we want to generate optical pulses in yellow-orange spectral range for green fluorescent protein (GFP) and yellow fluorescent protein (YFP) labelers, we find it difficult to obtain conventional OFAs at the corresponding fundamental wavelengths for SHG. In this report, we describe a novel method to generate smooth-shaped, sub-nanosecond, 586nm optical pulse sources toward STED application.

Original languageEnglish
Title of host publicationThe European Conference on Lasers and Electro-Optics, CLEO_Europe_2019
PublisherOSA - The Optical Society
ISBN (Electronic)9781557528209
Publication statusPublished - 2019
EventThe European Conference on Lasers and Electro-Optics, CLEO_Europe_2019 - Munich, Germany
Duration: 2019 Jun 232019 Jun 27

Publication series

NameOptics InfoBase Conference Papers
VolumePart F140-CLEO_Europe 2019

Conference

ConferenceThe European Conference on Lasers and Electro-Optics, CLEO_Europe_2019
CountryGermany
CityMunich
Period19/6/2319/6/27

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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