Generation of mercury-hyperaccumulating plants through transgenic expression of the bacterial mercury membrane transport protein MerC

Yoshito Sasaki, Takahiko Hayakawa, Chihiro Inoue, Atsushi Miyazaki, Simon Silver, Tomonobu Kusano

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

The merC gene from Acidithiobacillus ferrooxidans functions as a mercury uptake pump. MerC protein localizes in the cytoplasmic membrane of plant cells. When Arabidopsis thaliana and tobacco plants were transformed with the merC gene under the control of the Cauliflower mosaic virus 35S promoter, the resulting overexpression of merC rendered the host plants hypersensitive to Hg 2+ and they accumulated approximately twice as much Hg2+ ion as the wild type plants. Thus, bacterial mercuric ion transporters such as MerC may be useful molecular tools for producing transgenic plants that hyperaccumulate Hg2+ ion.

Original languageEnglish
Pages (from-to)615-625
Number of pages11
JournalTransgenic Research
Volume15
Issue number5
DOIs
Publication statusPublished - 2006 Oct 1

Keywords

  • Acidithiobacillus ferrooxidans
  • Arabidopsis
  • MerC
  • Mercury transporter
  • Phytoremediation
  • Tobacco

ASJC Scopus subject areas

  • Biotechnology
  • Animal Science and Zoology
  • Agronomy and Crop Science
  • Genetics

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