Generalized mucinosis in a patient with erythroderma

Taku Fujimura, Ryuhei Okuyama, Satoshi Nakagawa, Tadashi Terui, Setsuya Aiba

Research output: Contribution to journalArticlepeer-review

Abstract

We describe an 81-year-old Japanese patient with erythroderma overlapping with widespread and symmetrical deposits of mucin in the upper dermis. Clinically, the mucinous lesions on the nape and upper trunk were localized papular mucinosis. Histologically, there was a perivascular infiltrate of lymphohistiocytic cells mingled with plasma cells in the upper dermis but no sclerosis. Immunohistochemical staining revealed that more than 90% of these infiltrating plasma cells produced immunoglobulin λ-chain. Both the erythroderma and generalized mucinosis responded to topical steroid and PUVA therapy. To the best of our knowledge, this is the first case of erythroderma accompanied by generalized mucinosis.

Original languageEnglish
Pages (from-to)366-369
Number of pages4
JournalDermatology
Volume212
Issue number4
DOIs
Publication statusPublished - 2006 May

Keywords

  • Atypical papular mucinosis
  • Erythroderma

ASJC Scopus subject areas

  • Dermatology

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