A 7-month-old girl developed multiple nodules on her lower legs during the previous 1 month, and new lesions gradually appeared in her extremities. She presented with multiple nodules, several millimeters in diameter, chiefly located on the distal part of her extremities. Histopathological examination showed granulomas composed of epithelioid cells, multinucleated giant cells, and lymphocytes with mucin deposition between collagen fibers. From the clinicopathological findings, we diagnosed her as having generalized granuloma annulare. After a skin biopsy, the lesions began to resolve spontaneously. To our knowledge, she is the youngest case of generalized granuloma annulare in Japan.
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