Abstract
Indoles with oxygen-bearing substituents such as a methoxy or (triisopropylsilyl)oxy group at all of the positions of the benzene moiety were synthesized by cyclization of tert-butyl methoxy(or (triisopropylsilyl)oxy)-2-((trimethylsilyl)ethynyl)phenyl)carbamates with potassium tert-butoxide in tert-butyl alcohol. The (ethynylphenyl)carbamates were synthesized by the palladium-catalyzed reaction of (trimethylsilyl)acetylene and the corresponding (iodophenyl)carbamates, which were selectively synthesized by directed lithiation of the phenylcarbamates and subsequent iodination.
Original language | English |
---|---|
Pages (from-to) | 6507-6511 |
Number of pages | 5 |
Journal | Journal of Organic Chemistry |
Volume | 62 |
Issue number | 19 |
DOIs | |
Publication status | Published - 1997 Jan 1 |
ASJC Scopus subject areas
- Organic Chemistry