Gene transduction by sonoporation

Sho Ohta; Kentaro Suzuki; Yukiko Ogino; Shinichi Miyagawa; Aki Murashima; Daisuke Matsumaru; Gen Yamada

doi:10.1111/j.1440-169X.2008.01026.x

Gene transduction by sonoporation

Sho Ohta, Kentaro Suzuki, Yukiko Ogino, Shinichi Miyagawa, Aki Murashima, Daisuke Matsumaru, Gen Yamada

Research output: Contribution to journal › Short survey

28 Citations (Scopus)

Abstract

Gene transduction technologies are essential tools for understanding of gene functions or gene cascades underlying embryogenesis. In this review, we introduce a gene transduction method using microbubble and ultrasound (hereafter referred to as sonoporation). Sonoporation is carried out with relatively simple procedures and easily transduces genes into mesenchymal cells without significant damage to target tissues. Therefore, sonoporation is effective for gene transduction to study the molecular mechanisms of morphogenesis.

Original language	English
Pages (from-to)	517-520
Number of pages	4
Journal	Development Growth and Differentiation
Volume	50
Issue number	6
DOIs	https://doi.org/10.1111/j.1440-169X.2008.01026.x
Publication status	Published - 2008 Aug 1
Externally published	Yes

Keywords

Gene transduction chick
Limb bud
Microbubble
Sonoporation
Ultrasound

ASJC Scopus subject areas

Developmental Biology
Cell Biology

Access to Document

10.1111/j.1440-169X.2008.01026.x

Fingerprint Dive into the research topics of 'Gene transduction by sonoporation'. Together they form a unique fingerprint.

Cite this

Ohta, S., Suzuki, K., Ogino, Y., Miyagawa, S., Murashima, A., Matsumaru, D., & Yamada, G. (2008). Gene transduction by sonoporation. Development Growth and Differentiation, 50(6), 517-520. https://doi.org/10.1111/j.1440-169X.2008.01026.x

@article{e6eba60ee074408c9384024a6fdefdf7,

title = "Gene transduction by sonoporation",

abstract = "Gene transduction technologies are essential tools for understanding of gene functions or gene cascades underlying embryogenesis. In this review, we introduce a gene transduction method using microbubble and ultrasound (hereafter referred to as sonoporation). Sonoporation is carried out with relatively simple procedures and easily transduces genes into mesenchymal cells without significant damage to target tissues. Therefore, sonoporation is effective for gene transduction to study the molecular mechanisms of morphogenesis.",

keywords = "Gene transduction chick, Limb bud, Microbubble, Sonoporation, Ultrasound",

author = "Sho Ohta and Kentaro Suzuki and Yukiko Ogino and Shinichi Miyagawa and Aki Murashima and Daisuke Matsumaru and Gen Yamada",

year = "2008",

month = aug,

day = "1",

doi = "10.1111/j.1440-169X.2008.01026.x",

language = "English",

volume = "50",

pages = "517--520",

journal = "Development Growth and Differentiation",

issn = "0012-1592",

publisher = "Wiley-Blackwell",

number = "6",

}

TY - JOUR

T1 - Gene transduction by sonoporation

AU - Ohta, Sho

AU - Suzuki, Kentaro

AU - Ogino, Yukiko

AU - Miyagawa, Shinichi

AU - Murashima, Aki

AU - Matsumaru, Daisuke

AU - Yamada, Gen

PY - 2008/8/1

Y1 - 2008/8/1

N2 - Gene transduction technologies are essential tools for understanding of gene functions or gene cascades underlying embryogenesis. In this review, we introduce a gene transduction method using microbubble and ultrasound (hereafter referred to as sonoporation). Sonoporation is carried out with relatively simple procedures and easily transduces genes into mesenchymal cells without significant damage to target tissues. Therefore, sonoporation is effective for gene transduction to study the molecular mechanisms of morphogenesis.

AB - Gene transduction technologies are essential tools for understanding of gene functions or gene cascades underlying embryogenesis. In this review, we introduce a gene transduction method using microbubble and ultrasound (hereafter referred to as sonoporation). Sonoporation is carried out with relatively simple procedures and easily transduces genes into mesenchymal cells without significant damage to target tissues. Therefore, sonoporation is effective for gene transduction to study the molecular mechanisms of morphogenesis.

KW - Gene transduction chick

KW - Limb bud

KW - Microbubble

KW - Sonoporation

KW - Ultrasound

UR - http://www.scopus.com/inward/record.url?scp=50049134410&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=50049134410&partnerID=8YFLogxK

U2 - 10.1111/j.1440-169X.2008.01026.x

DO - 10.1111/j.1440-169X.2008.01026.x

M3 - Short survey

C2 - 18430029

AN - SCOPUS:50049134410

VL - 50

SP - 517

EP - 520

JO - Development Growth and Differentiation

JF - Development Growth and Differentiation

SN - 0012-1592

IS - 6

ER -