Abstract
Gene transduction technologies are essential tools for understanding of gene functions or gene cascades underlying embryogenesis. In this review, we introduce a gene transduction method using microbubble and ultrasound (hereafter referred to as sonoporation). Sonoporation is carried out with relatively simple procedures and easily transduces genes into mesenchymal cells without significant damage to target tissues. Therefore, sonoporation is effective for gene transduction to study the molecular mechanisms of morphogenesis.
Original language | English |
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Pages (from-to) | 517-520 |
Number of pages | 4 |
Journal | Development Growth and Differentiation |
Volume | 50 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2008 Aug 1 |
Externally published | Yes |
Keywords
- Gene transduction chick
- Limb bud
- Microbubble
- Sonoporation
- Ultrasound
ASJC Scopus subject areas
- Developmental Biology
- Cell Biology