Northern blot analysis showed transcripts of two types of the fibroblast growth factor (FGF) receptor genes, fig and bek, in almost all the tissues samples of 18 human gliomas and 22 human meningiomas, which produced abundant basic and/or acidic FGF. From immunohistochemistry, FGF receptors were expressed in the tumor cells of a glioma and a meningioma. RNA expression of these FGF receptors was also detectable in normal human brains and normal bovine meninges. The expression level of either FGF receptor gene was not significantly different between tumor tissues and normal tissues.
|Number of pages||7|
|Journal||Biochemical and biophysical research communications|
|Publication status||Published - 1991 May 31|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology