TY - JOUR
T1 - Gene expression of fibroblast growth factor receptors in the tissues of human gliomas and meningiomas
AU - Takahashi, Jun A.
AU - Suzui, Hiroshi
AU - Yasuda, Yosiko
AU - Ito, Nobuyuki
AU - Ohta, Mitsuhiro
AU - Jaye, Michael
AU - Fukumoto, Manabu
AU - Oda, Yoshifumi
AU - Kikuchi, Haruhiko
AU - Hatanaka, Masakazu
PY - 1991/5/31
Y1 - 1991/5/31
N2 - Northern blot analysis showed transcripts of two types of the fibroblast growth factor (FGF) receptor genes, fig and bek, in almost all the tissues samples of 18 human gliomas and 22 human meningiomas, which produced abundant basic and/or acidic FGF. From immunohistochemistry, FGF receptors were expressed in the tumor cells of a glioma and a meningioma. RNA expression of these FGF receptors was also detectable in normal human brains and normal bovine meninges. The expression level of either FGF receptor gene was not significantly different between tumor tissues and normal tissues.
AB - Northern blot analysis showed transcripts of two types of the fibroblast growth factor (FGF) receptor genes, fig and bek, in almost all the tissues samples of 18 human gliomas and 22 human meningiomas, which produced abundant basic and/or acidic FGF. From immunohistochemistry, FGF receptors were expressed in the tumor cells of a glioma and a meningioma. RNA expression of these FGF receptors was also detectable in normal human brains and normal bovine meninges. The expression level of either FGF receptor gene was not significantly different between tumor tissues and normal tissues.
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U2 - 10.1016/0006-291X(91)91939-A
DO - 10.1016/0006-291X(91)91939-A
M3 - Article
C2 - 1645953
AN - SCOPUS:0025911889
VL - 177
SP - 1
EP - 7
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
SN - 0006-291X
IS - 1
ER -