TY - JOUR
T1 - Gastric small cell carcinoma with marked response to neoadjuvant chemotherapy
AU - Nakamura, Yasuhiro
AU - Otani, Setsuya
AU - Otaka, Michiro
AU - Shimada, Tomoyuki
AU - Takahashi, Satsuki
AU - Saito, Masahiro
AU - Takahashi, Tohru
AU - Komatsu, Masahumi
AU - Suzuki, Toshie
AU - Okubo, Shunji
AU - Hayashi, Masato
AU - Sasano, Hironobu
PY - 2005/10
Y1 - 2005/10
N2 - We report a patient with gastric small cell carcinoma (SCC) who showed a marked response to neoadjuvant chemotherapy. The patient was a 72-year-old Japanese man who was admitted because of epigastralgia. Subsequent examination revealed the presence of advanced gastric carcinoma in the lesser curvature of the lower body of the stomach, with multiple abdominal lymph node metastases. Endoscopic biopsy specimens from the tumor revealed SCC with moderately differentiated adenocarcinoma. The patient received neoadjuvant chemotherapy consisting of carboplatin (400 mg/m2, for 1 day), epirubicin (27 mg/m2, for 1 day), etoposide (70 mg/m2, for 3 days), and 5-fluorouracil (330 mg/m2, for 11 days). Clinically, the primary tumor and lymph node metastases were markedly reduced. Subsequently the patient underwent curative surgery and was alive without recurrence for more than 3 years after the surgery.
AB - We report a patient with gastric small cell carcinoma (SCC) who showed a marked response to neoadjuvant chemotherapy. The patient was a 72-year-old Japanese man who was admitted because of epigastralgia. Subsequent examination revealed the presence of advanced gastric carcinoma in the lesser curvature of the lower body of the stomach, with multiple abdominal lymph node metastases. Endoscopic biopsy specimens from the tumor revealed SCC with moderately differentiated adenocarcinoma. The patient received neoadjuvant chemotherapy consisting of carboplatin (400 mg/m2, for 1 day), epirubicin (27 mg/m2, for 1 day), etoposide (70 mg/m2, for 3 days), and 5-fluorouracil (330 mg/m2, for 11 days). Clinically, the primary tumor and lymph node metastases were markedly reduced. Subsequently the patient underwent curative surgery and was alive without recurrence for more than 3 years after the surgery.
KW - Adenocarcinoma
KW - Neoadjuvant chemotherapy
KW - Small cell carcinoma
KW - Stomach
UR - http://www.scopus.com/inward/record.url?scp=27144511724&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=27144511724&partnerID=8YFLogxK
U2 - 10.1007/s10147-005-0492-y
DO - 10.1007/s10147-005-0492-y
M3 - Article
C2 - 16247663
AN - SCOPUS:27144511724
VL - 10
SP - 348
EP - 352
JO - International Journal of Clinical Oncology
JF - International Journal of Clinical Oncology
SN - 1341-9625
IS - 5
ER -