Galectin containing cells in the skin and mucosal tissues in Japanese conger eel, Conger myriaster: An immunohistochemical study

O. Nakamura, T. Watanabe, H. Kamiya, K. Muramoto

    Research output: Contribution to journalArticlepeer-review

    73 Citations (Scopus)

    Abstract

    Congerin is a β-galactoside binding lectin (galectin) purified from the skin mucus of the Japanese conger, Conger myriaster. To clarify its tissue distribution and productive cells, several tissue samples including skin, buccal cavity wall, tang, pharynx, gills, esophagus, stomach, intestine, liver, kidney, spleen and ovary of conger were stained immunohistochemically using polyclonal rabbit anti-congerin serum. In the epidermis, a number of club cells were strongly stained. Because no agglutinating activity was detected in plasma, it appears evident that congerin is produced and secreted into mucus by those cells. In addition, congerin-positive club cells were distributed in the mucosal epithelium lining the digestive tract preceding the stomach and in the gills. These findings suggest that congerin participates in innate immunity on the intra- and the extra-body surface of the conger. The putative functions of club cells in fish and their contained lectin are discussed.

    Original languageEnglish
    Pages (from-to)431-437
    Number of pages7
    JournalDevelopmental and Comparative Immunology
    Volume25
    Issue number5-6
    DOIs
    Publication statusPublished - 2001 Jun

    Keywords

    • Alimentary canal
    • Anguilliformes
    • Club cell
    • Galectin
    • Immunohistochemistry
    • Japanese conger
    • Mucosal epithelium
    • Skin mucus

    ASJC Scopus subject areas

    • Immunology
    • Developmental Biology

    Fingerprint Dive into the research topics of 'Galectin containing cells in the skin and mucosal tissues in Japanese conger eel, Conger myriaster: An immunohistochemical study'. Together they form a unique fingerprint.

    Cite this