TY - JOUR
T1 - Functionalized Fullerenes in Water. The First 10 Years of Their Chemistry, Biology, and Nanoscience
AU - Nakamura, Eiichi
AU - Isobe, Hiroyuki
PY - 2003/11/1
Y1 - 2003/11/1
N2 - Fullerenes are entirely insoluble in water, but suitable functionalization makes the molecules soluble. Studies on water-soluble fullerene derivatives led to the discovery of the interaction of organofullerenes with DNA, proteins, and living cells, which was first reported in the summer of 1993. Subsequent studies have revealed interesting biological activity aspects of organofullerenes owing to their photochemistry, radical quenching, and hydrophobicity to form one- to three-dimensional supramolecular complexes. In these areas of research, synthetic organic chemistry has played an important role in the creation of tailor-made molecules.
AB - Fullerenes are entirely insoluble in water, but suitable functionalization makes the molecules soluble. Studies on water-soluble fullerene derivatives led to the discovery of the interaction of organofullerenes with DNA, proteins, and living cells, which was first reported in the summer of 1993. Subsequent studies have revealed interesting biological activity aspects of organofullerenes owing to their photochemistry, radical quenching, and hydrophobicity to form one- to three-dimensional supramolecular complexes. In these areas of research, synthetic organic chemistry has played an important role in the creation of tailor-made molecules.
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U2 - 10.1021/ar030027y
DO - 10.1021/ar030027y
M3 - Article
C2 - 14622027
AN - SCOPUS:0344393787
VL - 36
SP - 807
EP - 815
JO - Accounts of Chemical Research
JF - Accounts of Chemical Research
SN - 0001-4842
IS - 11
ER -