Abstract
Magnetic composite nanoparticles of gold and iron-oxide synthesized with gamma-rays or ultrasonics were functionalized with thiol-modified oligonucleotides. The amount of oligonucleotides bound to the functionalized nanoparticle probes via hybridization was quantified with fluorescently-labeled target oligonucleotides. Our composite nanoparticles magnetically separated the specific target oligonucleotides without the non-specific adsorption.
| Original language | English |
|---|---|
| Pages (from-to) | 255-258 |
| Number of pages | 4 |
| Journal | Journal of Magnetism and Magnetic Materials |
| Volume | 311 |
| Issue number | 1 SPEC. ISS. |
| DOIs | |
| Publication status | Published - 2007 Apr |
Keywords
- Composite nanoparticle
- Gold
- Iron-oxide
- Magnetic separation
- Oligonucleotide
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
Fingerprint Dive into the research topics of 'Functionalization of magnetic gold/iron-oxide composite nanoparticles with oligonucleotides and magnetic separation of specific target'. Together they form a unique fingerprint.
Cite this
Kinoshita, T., Seino, S., Mizukoshi, Y., Nakagawa, T., & Yamamoto, T. A. (2007). Functionalization of magnetic gold/iron-oxide composite nanoparticles with oligonucleotides and magnetic separation of specific target. Journal of Magnetism and Magnetic Materials, 311(1 SPEC. ISS.), 255-258. https://doi.org/10.1016/j.jmmm.2006.10.1161