Abstract
Magnetic composite nanoparticles of gold and iron-oxide synthesized with gamma-rays or ultrasonics were functionalized with thiol-modified oligonucleotides. The amount of oligonucleotides bound to the functionalized nanoparticle probes via hybridization was quantified with fluorescently-labeled target oligonucleotides. Our composite nanoparticles magnetically separated the specific target oligonucleotides without the non-specific adsorption.
Original language | English |
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Pages (from-to) | 255-258 |
Number of pages | 4 |
Journal | Journal of Magnetism and Magnetic Materials |
Volume | 311 |
Issue number | 1 SPEC. ISS. |
DOIs | |
Publication status | Published - 2007 Apr |
Keywords
- Composite nanoparticle
- Gold
- Iron-oxide
- Magnetic separation
- Oligonucleotide
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics