Functional regulation of biomolecule using DNA-conjugation.

Takahisa Anada; Takeshi Kano; Wataru Kaku; Yoshiki Katayama; Mizuo Maeda; Masaharu Murata

doi:10.1093/nass/2.1.269

Functional regulation of biomolecule using DNA-conjugation.

Takahisa Anada, Takeshi Kano, Wataru Kaku, Yoshiki Katayama, Mizuo Maeda, Masaharu Murata

DEN - Dental Sciences

Research output: Contribution to journal › Article

2 Citations (Scopus)

Abstract

3'-methacryloyl-oligodeoxynucleotide having antisense sequence against messenger RNA of green fluorescent protein and N-isopropylacrylamide were co-polymerized. The conjugate can reversibly change its conformation at around a transition temperature, similarly to N-isopropylacrylamide homopolymer. We achieved artificially regulation of gene expression depending on temperature using the conjugate.

Original language	English
Pages (from-to)	269-270
Number of pages	2
Journal	Nucleic acids research. Supplement (2001)
Issue number	2
DOIs	https://doi.org/10.1093/nass/2.1.269
Publication status	Published - 2002

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Anada, T., Kano, T., Kaku, W., Katayama, Y., Maeda, M., & Murata, M. (2002). Functional regulation of biomolecule using DNA-conjugation. Nucleic acids research. Supplement (2001), (2), 269-270. https://doi.org/10.1093/nass/2.1.269

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AU - Maeda, Mizuo

AU - Murata, Masaharu

PY - 2002

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