Functional regulation of biomolecule using DNA-conjugation.

Takahisa Anada; Takeshi Kano; Wataru Kaku; Yoshiki Katayama; Mizuo Maeda; Masaharu Murata

doi:10.1093/nass/2.1.269

Functional regulation of biomolecule using DNA-conjugation.

Takahisa Anada, Takeshi Kano, Wataru Kaku, Yoshiki Katayama, Mizuo Maeda, Masaharu Murata

DEN - Dental Sciences

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

3'-methacryloyl-oligodeoxynucleotide having antisense sequence against messenger RNA of green fluorescent protein and N-isopropylacrylamide were co-polymerized. The conjugate can reversibly change its conformation at around a transition temperature, similarly to N-isopropylacrylamide homopolymer. We achieved artificially regulation of gene expression depending on temperature using the conjugate.

Original language	English
Pages (from-to)	269-270
Number of pages	2
Journal	Nucleic acids research. Supplement (2001)
Issue number	2
DOIs	https://doi.org/10.1093/nass/2.1.269
Publication status	Published - 2002

ASJC Scopus subject areas

Medicine(all)

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10.1093/nass/2.1.269

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title = "Functional regulation of biomolecule using DNA-conjugation.",

abstract = "3'-methacryloyl-oligodeoxynucleotide having antisense sequence against messenger RNA of green fluorescent protein and N-isopropylacrylamide were co-polymerized. The conjugate can reversibly change its conformation at around a transition temperature, similarly to N-isopropylacrylamide homopolymer. We achieved artificially regulation of gene expression depending on temperature using the conjugate.",

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T1 - Functional regulation of biomolecule using DNA-conjugation.

AU - Anada, Takahisa

AU - Kano, Takeshi

AU - Kaku, Wataru

AU - Katayama, Yoshiki

AU - Maeda, Mizuo

AU - Murata, Masaharu

PY - 2002

Y1 - 2002

N2 - 3'-methacryloyl-oligodeoxynucleotide having antisense sequence against messenger RNA of green fluorescent protein and N-isopropylacrylamide were co-polymerized. The conjugate can reversibly change its conformation at around a transition temperature, similarly to N-isopropylacrylamide homopolymer. We achieved artificially regulation of gene expression depending on temperature using the conjugate.

AB - 3'-methacryloyl-oligodeoxynucleotide having antisense sequence against messenger RNA of green fluorescent protein and N-isopropylacrylamide were co-polymerized. The conjugate can reversibly change its conformation at around a transition temperature, similarly to N-isopropylacrylamide homopolymer. We achieved artificially regulation of gene expression depending on temperature using the conjugate.

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DO - 10.1093/nass/2.1.269

M3 - Article

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JO - Nucleic acids research. Supplement (2001)

JF - Nucleic acids research. Supplement (2001)

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ER -

Functional regulation of biomolecule using DNA-conjugation.

Abstract

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