Abstract
3'-methacryloyl-oligodeoxynucleotide having antisense sequence against messenger RNA of green fluorescent protein and N-isopropylacrylamide were co-polymerized. The conjugate can reversibly change its conformation at around a transition temperature, similarly to N-isopropylacrylamide homopolymer. We achieved artificially regulation of gene expression depending on temperature using the conjugate.
Original language | English |
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Pages (from-to) | 269-270 |
Number of pages | 2 |
Journal | Nucleic acids research. Supplement (2001) |
Issue number | 2 |
DOIs | |
Publication status | Published - 2002 |
ASJC Scopus subject areas
- Medicine(all)