Abstract
Nucleic acid analogs were prepared by grafting cytosine and hypoxanthine derivatives containing hydroxyl groups onto linear polyethyleneimine. The polymers contained about 90 unit mol% of the nucleic acid bases, and were easily soluble in water at neutral pH value. They were found to form polymer complexes with polynucleotides (PolyI and PolyC) by specific base-base interactions in aqueous solution.
Original language | English |
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Pages (from-to) | 11-18 |
Number of pages | 8 |
Journal | Polymer Journal |
Volume | 21 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1989 Jan 1 |
Externally published | Yes |
Keywords
- Cytosine
- Homoserine
- Hypoxanthine
- Nucleic acid analogs
- Polyc
- Polyethyleneimine
- Polyl
- Polymer complex
- Specific interaction
- Water soluble polymer
ASJC Scopus subject areas
- Polymers and Plastics
- Materials Chemistry