Functional monomers and polymers clxxi. Synthesis and interaction studies on water soluble nucleic acid analogs: Polyethyleneimine derivatives containing cytosine and hypoxanthine

Takehiko Wada, Yoshiaki Inaki, Kiichi Takemoto

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Nucleic acid analogs were prepared by grafting cytosine and hypoxanthine derivatives containing hydroxyl groups onto linear polyethyleneimine. The polymers contained about 90 unit mol% of the nucleic acid bases, and were easily soluble in water at neutral pH value. They were found to form polymer complexes with polynucleotides (PolyI and PolyC) by specific base-base interactions in aqueous solution.

Original languageEnglish
Pages (from-to)11-18
Number of pages8
JournalPolymer Journal
Volume21
Issue number1
DOIs
Publication statusPublished - 1989 Jan 1
Externally publishedYes

Keywords

  • Cytosine
  • Homoserine
  • Hypoxanthine
  • Nucleic acid analogs
  • Polyc
  • Polyethyleneimine
  • Polyl
  • Polymer complex
  • Specific interaction
  • Water soluble polymer

ASJC Scopus subject areas

  • Polymers and Plastics
  • Materials Chemistry

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