TY - JOUR
T1 - Functional hydration behavior
T2 - Interrelation between hydration and molecular properties at lipid membrane interfaces
AU - Watanabe, Nozomi
AU - Suga, Keishi
AU - Umakoshi, Hiroshi
N1 - Funding Information:
-is work was primarily supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI Grant-in-Aids for Scientific Research (A) (26249116), Grant-in-Aids for Young Scientists (B) (16K18279), Grant-in-Aids for Challenging Exploratory Research (T15K142040), and Grant-in-Aids for Research Fellow (JP18J11666).
Publisher Copyright:
© 2019 Nozomi Watanabe et al.
PY - 2019
Y1 - 2019
N2 - Water is an abundant commodity and has various important functions. It stabilizes the structure of biological macromolecules, controls biochemical activities, and regulates interfacial/intermolecular interactions. Common aspects of interfacial water can be obtained by overviewing fundamental functions and properties at different temporal and spatial scales. It is important to understand the hydrogen bonding and structural properties of water and to evaluate the individual molecular species having different hydration properties. Water molecules form hydrogen bonds with biomolecules and contribute to the adjustment of their properties, such as surface charge, hydrophilicity, and structural flexibility. In this review, the fundamental properties of water molecules and the methods used for the analyses of water dynamics are summarized. In particular, the interrelation between the hydration properties, determined by molecules, and the properties of molecules, determined by their hydration properties, are discussed using the lipid membrane as an example. Accordingly, interesting water functions are introduced that provide beneficial information in the fields of biochemistry, medicine, and food chemistry.
AB - Water is an abundant commodity and has various important functions. It stabilizes the structure of biological macromolecules, controls biochemical activities, and regulates interfacial/intermolecular interactions. Common aspects of interfacial water can be obtained by overviewing fundamental functions and properties at different temporal and spatial scales. It is important to understand the hydrogen bonding and structural properties of water and to evaluate the individual molecular species having different hydration properties. Water molecules form hydrogen bonds with biomolecules and contribute to the adjustment of their properties, such as surface charge, hydrophilicity, and structural flexibility. In this review, the fundamental properties of water molecules and the methods used for the analyses of water dynamics are summarized. In particular, the interrelation between the hydration properties, determined by molecules, and the properties of molecules, determined by their hydration properties, are discussed using the lipid membrane as an example. Accordingly, interesting water functions are introduced that provide beneficial information in the fields of biochemistry, medicine, and food chemistry.
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U2 - 10.1155/2019/4867327
DO - 10.1155/2019/4867327
M3 - Review article
AN - SCOPUS:85060788795
VL - 2019
JO - E-Journal of Chemistry
JF - E-Journal of Chemistry
SN - 2090-9063
M1 - 4867327
ER -